Prevalence of hereditary ataxias and spastic paraplegias in Molise,a region of Italy |
| |
Authors: | Alessandro Filla Giuseppe De Michele Roberto Marconi Luigi Bucci Carmine Carillo Anna Elisa Castellano Lucio Iorio Claudio Kniahynicki Francesco Rossi Giuseppe Campanella |
| |
Affiliation: | (1) Department of Neurology, Second School of Medicine, University of Naples, Via Pansini, 5, 1-80131 Naples, Italy;(2) Neurological Institute Sanatrix, Venafro, Italy |
| |
Abstract: | Summary An epidemiological survey of hereditary ataxias and paraplegias was conducted in Molise, a region of Italy (335, 211 inhabitants on 1 January 1989). Total prevalence was 7.5 x 10–5 inhabitants (95% confidence limits 4.8–11.1). There were 7 patients with Friedreich's disease, 5 with early onset cerebellar ataxia with retained tendon reflexes, 4 with ataxia-telangiectasia, 9 with hereditary spastic paraplegias (2 autosomal dominant and 7 autosomal recessive cases). There was no patient with autosomal dominant cerebellar ataxia. |
| |
Keywords: | Epidemiology Hereditary ataxias Hereditary spastic paraplegias |
本文献已被 SpringerLink 等数据库收录! |
|