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Systemic contact dermatitis from subcutaneous hydromorphone
Authors:Christa   de Cuyper Marleen  Goeteyn
Affiliation:Department of Dermatology, A. Z. Sint-Jan, Brugge, Belgium.
Abstract:
We report a patient who developed a generalized dermatitis after a period of progressive local intolerance to continuous subcutaneous infusion of hydromorphone for cancer pain. Sensitization to hydromorphone was proved by a positive patch test. Infusions with an equianalgesic dose of diacetylmorphine were well tolerated, without local or systemic side-effects, and prolonged the duration of infusion sites.
Keywords:allergic contact dermatitis    plants    Frullania    frullanolide    sesquiterpene lactone    patch testing    active sensitization    patch testing technique    occupational    airborne contact dermatitis
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