| 优化合成苄氧基苯甲醛的反应条件 |
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| 引用本文： | 刘静姿,史大斌,李魏林.优化合成苄氧基苯甲醛的反应条件[J].遵义医学院学报,2007,30(2):121-122,125. |
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| 作者姓名： | 刘静姿 史大斌 李魏林 |
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| 作者单位： | 1. 遵义医学院,药学系药物化学教研室,贵州,遵义,563003
2. 贵州大学化学学院,贵州,贵阳,550000 |
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| 摘 要： | 目的 研究微波合成苄氧基苯甲醛的最佳反应条件。方法 利用微波加热研究微波输出功率，辐射时间及不同溶剂对反应速度及收率的影响，同时与常规加热反应的时间、收率做对比。结果 目标物结构经IR，MS，1HNMR确证，合成了苄氧基苯甲醛类化合物。结论 与常规加热法相比较，反应速度快，收率高，操作简便。微波辐射对合成苄氧基苯甲醛有显著的催化作用，选择适当的微波辐射条件是获得较高收率的主要原因之一。
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| 关 键 词： | 苄氧基苯甲醛 微波辐射 有机合成 药物中间体 |
| 文章编号： | 1000-2715（2007）02-0121-02 |
| 收稿时间： | 2006-10-15 |
| 修稿时间： | 2006-10-15 |
Optimize the react conditions of synthesis of benzyloxy-benzaldehyde |
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| LIU Jing-zi,SHI Da-bin,LI Wei-lin.Optimize the react conditions of synthesis of benzyloxy-benzaldehyde[J].Acta Academiae Medicine Zunyi,2007,30(2):121-122,125. |
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| Authors: | LIU Jing-zi SHI Da-bin LI Wei-lin |
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| Institution: | 1.Department of pharmic Chemistry, Zunyi Medical College, Zunyi Guizou 563003, China ; 2.The Faculty of Chemistry, Guizhou Univercity, Guizhou Guiyang 550000, China |
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| Abstract: | Objective To study Optimization of the react conditions of benzyloxy-benzaldehyde synthesized under microwave irradiation. Methods The effects of microwave power, irradiation time and different solvents on the reaction were dicussed, In addition, Compared with the conventional heating reaction. Results The structures of the compound were characterized by elemental analysis, MS, IR and 1HNMR. Conclusions The method has advantage of high yield, short reaction time and simple in operation. Microwave irradiation to the reaction has striking catalystic action, the main reasons that the choice of microwave conditions were efficient. |
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| Keywords: | benzyloxy-benzaldehyde microwave irradiation synthesis organic |
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