可疑早期老年性黄斑变性黄斑光阈值短期波动的研究

目的 研究Octopus-123视野计对视力正常的可疑早期老年性黄斑变性(age-related macular degeneration,AMD)光阈值短期波动(short-term fluctuation,SF)的检测意义。 方法 对可疑早期AMD患者51例66只眼，正常对照32人40只眼，进行黄斑光阈值SF、Amsler表和中心视力的检测。 结果 可疑早期AMD患者与正常对照组的SF比较差异有显著性的意义，且较中心视力及Amsler表检查更为敏感。SF与玻璃膜疣的数量、部位和性质有关。 结论 部分中心视力正常、眼底有玻璃膜疣的可疑早期AMD，视功能已发生改变。 (中华眼底病杂志, 2002, 119-120)

A study on the short-term fluctuation of macular light threshold in suspected early age-related macular dege-neration

Objective To study the significance of detection the short term fluctuation ( SF) of macular light threshold detected by Octopus 123 automatic perimeter in suspected early age related macular dege neration (AMD). Methods SF of macular light sensitivity, Amsler chart and central visual acuity were examined in 51 patients(66 eyes) with suspected early AMD group and in 32 patients (40 eyes) in the control group. Results SF were significantly different in suspected early AMD group and control group. SF was more sensitive than the examination of central visual acuity and Amsler chart. SF was related to the quantity, location and quality of drusen. Conclusion Visual function of some suspected early AMD patients with drusen may be damaged, though the central visual acuity appears normal.