The impact of the Catechol-O-methyltransferase Val158Met polymorphism on survival in the general population – the HUNT study |
| |
| Authors: | Knut Hagen Lars J Stovner Frank Skorpen Elin Pettersen John-Anker Zwart |
| |
| Institution: | (1) Department of Clinical Neuroscience, Faculty of medicine, Norwegian University of Science and Technology, Trondheim, Norway;(2) Norwegian National Headache Centre, Section of Neurology, St. Olavs Hospital, Trondheim, Norway;(3) Department of Laboratory Medicine, Children's and Women's health, Faculty of medicine, Norwegian University of Science and Technology, Trondheim, Norway;(4) National Centre for Spinal Disorders, St. Olavs Hospital, Trondheim, Norway |
| |
| Abstract: | Background The catechol-O-methyltransferase (COMT) gene contains a functional polymorphism, Val158Met which has been related to common diseases like cancer, psychiatric illness
and myocardial infarction. Whether the Val158Met polymorphism is associated with survival has not been evaluated in the general
population. The aim of this prospective study was to evaluate the impact of codon 158 COMT gene polymorphism on survival in a population-based cohort. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
