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桑叶对小白鼠的镇咳作用实验研究
引用本文:周绍坚,苏湘敏,陈华俊,黄丽,莫瑞琴,罗莹,薛强,许小林. 桑叶对小白鼠的镇咳作用实验研究[J]. 右江民族医学院学报, 2007, 29(5): 697-698
作者姓名:周绍坚  苏湘敏  陈华俊  黄丽  莫瑞琴  罗莹  薛强  许小林
作者单位:1. 右江民族医学院2004级检验本科,广西,百色,533000
2. 右江民族医学院药理学教研室,广西,百色,533000
3. 右江民族医学院药学教研室,广西,百色,533000
摘    要:
目的观察桑叶对小白鼠的镇咳作用。方法将50只小白鼠随机分成5组,每组10只,即阳性对照组(复方甘草口服溶液0.1ml/10g)、桑叶大、中、小浓度组(剂量均为0.1ml/10g),阴性对照组(生理盐水0.1ml/10g);采用氨水引咳法引发小白鼠咳嗽,观察小白鼠的咳嗽潜伏期及1min内的咳嗽次数。结果大、中、小桑叶组均能延长小白鼠咳嗽潜伏期及减少每一分钟内的咳嗽次数(P<0.01)。结论桑叶对小白鼠具有镇咳作用。

关 键 词:桑叶  镇咳  小白鼠  动物,实验
文章编号:1001-5817(2007)05-0697-02
收稿时间:2007-03-08
修稿时间:2007-03-08

A laboratory study of anti - cough effects of Morus alba leaves on white mice
ZHOU Shao-jian,SU Xiang-min,CHEN Hua-jun,HUANG Li,MO Rui-qin,LUO Ying,XUE Qiang,Xu Xiao-lin. A laboratory study of anti - cough effects of Morus alba leaves on white mice[J]. Journal of Youjiang Medical College For Nationalities, 2007, 29(5): 697-698
Authors:ZHOU Shao-jian  SU Xiang-min  CHEN Hua-jun  HUANG Li  MO Rui-qin  LUO Ying  XUE Qiang  Xu Xiao-lin
Affiliation:1. Grade 2004, Department of Laboratory Medicine, Youjiang Medical College for Nationalities, Baise , Guangxi 533000, China ; 2. Department of Pharmacology, Youjiang Medical College for Nationalities, Baise, Guangxi 533000, China; 3. Department of Pharmacy, Youjiang Medical College for Nationalities, Baise, Guangxi 533000, China
Abstract:
Objective To examine the anti-cough effect of Morus alba leaves (MAL) on white mice.Methods 50 white mice were randomle allocated to 5 groups,10 in each group: a positive control group(given Compound Liquorice Oral Liquid 0.1ml/10g),and high,medium,low concentrations of MAL groups(all the dosage were 0.1ml/10g),and a negative control group(normal saline 0.1ml/10g).The white mice with cough were induced by giving ammonia water.The latency of cough and the cough times with 1 minute were observed.Results In high,medium and low concentrations of MAL groups,the cough latency was prolonged and the cough times were reduced within 1 minute(P<0.01).Conclusion MAL is effective on white mice with cough induced by ammonia water.
Keywords:Morus alba leaves   anti-cough   white mice   animals, laboratory
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