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国产阿齐霉素治疗细菌感染207例临床研究
引用本文:盛吉芳,郑经川,干梦九,俞云松,严杰. 国产阿齐霉素治疗细菌感染207例临床研究[J]. 浙江大学学报(医学版), 1998, 0(2)
作者姓名:盛吉芳  郑经川  干梦九  俞云松  严杰
作者单位:浙江医科大学附属第一医院传染病科(盛吉芳,郑经川,干梦九,俞云松),浙江医科大学微生物学教研室(严杰)
摘    要:目的:了解国产阿齐霉素与进口阿齐霉素的疗效和不良反应。方法:选择207例细菌性感染疾病患者,其中107例用国产阿齐霉素片治疗者与100例用进口阿齐霉素胶囊治疗者进行随机对照观察。结果:两组痊愈率分别为52.34%和63.00%,有效率各为93.46%和92.00%,两组临床症状、体征消退时间相似.两组细菌消除率分别为96.43%和94.00%,不良反应发生率均少而轻微,分别为1.87%和1.00%。结论:国产阿齐霉素片治疗细菌性感染与进口阿齐霉素胶囊同样安全有效。

关 键 词:阿齐霉素/治疗应用  阿齐霉素/副作用  细菌感染/药物疗法

Comparative Study of 207 Cases with Bacterial Infections Treated with Domestic and Imported Azithromycin(AZI)
Sheng Jifang,Zheng Jiangchuan,Gan Mengjiu, et al. Comparative Study of 207 Cases with Bacterial Infections Treated with Domestic and Imported Azithromycin(AZI)[J]. Journal of Zhejiang University. Medical sciences, 1998, 0(2)
Authors:Sheng Jifang  Zheng Jiangchuan  Gan Mengjiu   et al
Affiliation:The First Affiliated Hospital of ZhejiangMedical University
Abstract:Objective To compare the efficacy and side effects of the domestic AZI and imported AZI. Me thods: A randomized comparative study was carried out in 207 patients with bacterial infections. 107 of whomwere treated with domestic AZI and 100 patients with imported AZI (Pliva). Results:The cure rate .total effective rate and bacterial elimination rate were 52. 34 %, 93. 46 %, 96. 43 % and 63. 00%. 92. 00%, 94. 00% respectively for the two groups;no significant difference was found. The recovery time of symptoms and signs was similar in the two groups. The side effects for the two groups were 1. 87% and 1. 00%. Conclusion: The domesticAZI is as effective and safe as the imported AZI in treatment of bacterial infection.
Keywords:Azithromycin/ther us  Azithromycin/adv eff  Bacterial infection/drug ther  
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