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Timely awareness and prevention of emerging chemical and biochemical risks in foods: Proposal for a strategy based on experience with recent cases
Authors:G.A. Kleter  M.J. Groot  M. Poelman  E.J. Kok  H.J.P. Marvin
Affiliation:1. RIKILT – Institute of Food Safety, Wageningen University and Research Center, P.O. Box 230, NL-6700 AE Wageningen, The Netherlands;2. IMARES – Institute of Marine Resources and Ecosystem Studies, Wageningen University and Research Center, P.O. Box 77, NL-4400 AB Yerseke, The Netherlands
Abstract:
A number of recent food safety incidents have involved chemical substances, while various activities aim at the early identification of emerging chemical risks. This review considers recent cases of chemical and biochemical risks, as a basis for recommendations for awareness and prevention of similar risks at an early stage. These cases include examples of unapproved genetically modified food crops, intoxications with botanical products containing unintentionally admixed toxic herbs, residues of unapproved antibiotics and contaminants in farmed aquaculture species such as shrimp and salmon; and adverse effects of chemical and biological pesticides of natural origin. Besides case-specific recommendations for mitigation of future incidents of the same nature, general inferences and recommendations are made. It is recommended, for example, to establish databases for contaminants potentially present within products. Pro-active reconnaissance can facilitate the identification of products potentially contaminated with hazardous substances. In international trade, prevention and early identification of hazards are aided by management systems for product quality and safety, rigorous legislation, and inspections of consignments destined for export. Cooperation with the private sector and foreign authorities may be required to achieve these goals. While food and feed safety are viewed from the European perspective, the outcomes also apply to other regions.
Keywords:ADI, acceptable daily intake   APHIS, Animal and Plant Health Inspection Service   BEN, Balkan endemic nephropathy   CAP, chloramphenicol   CDC, center for Disease Control and Prevention   CHN, Chinese herb nephropathy   DNA, deoxyribonucleic acid   EC, European Community   Cry protein, protein from crystalline inclusions of spores formed by Bacillus thuringiensis   EFSA, European Food Safety Authority   EMEA, European Agency for the Registration of Medicinal Products   EMRISK, EFSA-sponsored project on forming a global system for identifying food-related emerging risks   EPA, Environmental Protection Agency   ERA, environmental risk assessment   EU, European Union   Eurostat, Statistical Office of the European Communities   FAO, Food and Agriculture Organization of the United Nations   FDA, Food and Drug Administration   FIFRA, federal insecticide fungicide and rodenticide act   GABA, γ-aminobutyric acid   GC, gas chromatography   GM, genetically modified   GMO, GM organism   GRAS, generally recognized as safe   HACCP, hazard analysis critical control points   HMPC, committee on herbal medicinal products   HPLC, high-performance liquid chromatography   ISO, International Standards Organization   JECFA, Joint FAO/WHO Expert Committee on Food Additives   MPP+, 1-methyl-4-phenylpyridinium   MPTP, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine   MRL, maximum residue level   MRPL, minimally required performance level   MS, mass spectrometry   PeriApt, EU-project on pan-European pro-active identification of emerging risks in the field of food production   SAP, scientific advisory panel   TGEV, transmissible gastroenteritis virus   TLC, thin-layer chromatography   UK, United Kingdom   US, United States   USDA, US Department of Agriculture   WHO, World Health Organization.
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