Timely awareness and prevention of emerging chemical and biochemical risks in foods: Proposal for a strategy based on experience with recent cases |
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Authors: | G.A. Kleter M.J. Groot M. Poelman E.J. Kok H.J.P. Marvin |
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Affiliation: | 1. RIKILT – Institute of Food Safety, Wageningen University and Research Center, P.O. Box 230, NL-6700 AE Wageningen, The Netherlands;2. IMARES – Institute of Marine Resources and Ecosystem Studies, Wageningen University and Research Center, P.O. Box 77, NL-4400 AB Yerseke, The Netherlands |
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Abstract: | ![]() A number of recent food safety incidents have involved chemical substances, while various activities aim at the early identification of emerging chemical risks. This review considers recent cases of chemical and biochemical risks, as a basis for recommendations for awareness and prevention of similar risks at an early stage. These cases include examples of unapproved genetically modified food crops, intoxications with botanical products containing unintentionally admixed toxic herbs, residues of unapproved antibiotics and contaminants in farmed aquaculture species such as shrimp and salmon; and adverse effects of chemical and biological pesticides of natural origin. Besides case-specific recommendations for mitigation of future incidents of the same nature, general inferences and recommendations are made. It is recommended, for example, to establish databases for contaminants potentially present within products. Pro-active reconnaissance can facilitate the identification of products potentially contaminated with hazardous substances. In international trade, prevention and early identification of hazards are aided by management systems for product quality and safety, rigorous legislation, and inspections of consignments destined for export. Cooperation with the private sector and foreign authorities may be required to achieve these goals. While food and feed safety are viewed from the European perspective, the outcomes also apply to other regions. |
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Keywords: | ADI, acceptable daily intake APHIS, Animal and Plant Health Inspection Service BEN, Balkan endemic nephropathy CAP, chloramphenicol CDC, center for Disease Control and Prevention CHN, Chinese herb nephropathy DNA, deoxyribonucleic acid EC, European Community Cry protein, protein from crystalline inclusions of spores formed by Bacillus thuringiensis EFSA, European Food Safety Authority EMEA, European Agency for the Registration of Medicinal Products EMRISK, EFSA-sponsored project on forming a global system for identifying food-related emerging risks EPA, Environmental Protection Agency ERA, environmental risk assessment EU, European Union Eurostat, Statistical Office of the European Communities FAO, Food and Agriculture Organization of the United Nations FDA, Food and Drug Administration FIFRA, federal insecticide fungicide and rodenticide act GABA, γ-aminobutyric acid GC, gas chromatography GM, genetically modified GMO, GM organism GRAS, generally recognized as safe HACCP, hazard analysis critical control points HMPC, committee on herbal medicinal products HPLC, high-performance liquid chromatography ISO, International Standards Organization JECFA, Joint FAO/WHO Expert Committee on Food Additives MPP+, 1-methyl-4-phenylpyridinium MPTP, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine MRL, maximum residue level MRPL, minimally required performance level MS, mass spectrometry PeriApt, EU-project on pan-European pro-active identification of emerging risks in the field of food production SAP, scientific advisory panel TGEV, transmissible gastroenteritis virus TLC, thin-layer chromatography UK, United Kingdom US, United States USDA, US Department of Agriculture WHO, World Health Organization. |
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