抗感染活性骨一期植骨治疗股骨慢性创伤性骨髓炎的疗效分析

目的 验证抗感染活性骨(ARBX)一期同步植骨治疗股骨慢性创伤性骨髓炎的疗效. 方法自2001年9月至2008年9月,采用ARBX一期同步植骨治疗股骨慢性创伤性骨髓炎24例,对其中获得10个月以上系统随访的18例患者进行疗效分析. 结果随访时间10～63个月,平均23个月.18例患者除3例骨髓炎未治愈外,其余15例骨髓炎完全治愈:感染彻底控制无复发,骨不连、骨缺损获得骨修复.本组完全治愈率为83.3%. 结论 ARBX具有高效诱导成骨活性和强效抗感染能力.能一期植骨有效治疗股骨慢性创伤性骨髓炎.

Anti-infective reconstituted bone xenograft in one-stage treatment of posttraumatic osteomyelitis of the femur

Objective To study the efficacy of anti-infective reconstituted bone xenograft (ARBX) in one-stage treatment of posttraumatie osteomyelitis of the femur. Methods From September 2001 to September 2008, 24 cases of posttraumatic osteomyelitis of the femur were treated with simultaneous one-stage grafting of ARBX after debridement. A retrospective study was done for the 18 cases of them who had been followed up for an average of 23 ( 10 to 63) months. Results In 3 cases, the infection was out of control or recurred, while in the other 15 cases, the infection, nonunion and bony defects were cured without reoccurrence. The rate of complete cure was 83.3% for this group, higher than that for conventional therapy. Conclusion Since ARBX is highly effective in inducing osteogenic activity and capable of resisting infection, it can be used in simultaneous one-stage grafting for treatment of patients with posttraumatic osteomyelitis of the femur.