首页 | 本学科首页   官方微博 | 高级检索  
检索        

28例路易体痴呆患者的视频-多导睡眠图分析
引用本文:彭全,施海姗,侯乐,卢慧贤,宁玉萍.28例路易体痴呆患者的视频-多导睡眠图分析[J].神经疾病与精神卫生,2013(5):464-467.
作者姓名:彭全  施海姗  侯乐  卢慧贤  宁玉萍
作者单位:东莞东华医院神经内科,523110
基金项目:广州市医药卫生科技项目(2012A011070019);广州市医药卫生科技项目(201102A213183);广州市中医药科技项目(201122231038)
摘    要:目的研究路易体痴呆(DLB)患者的视频~多导睡眠图,探讨路易体痴呆患者的睡眠结构。方法对临床诊断DLB28例及正常对照28人进行研究。所有入组者均进行简易精神状态检查量表(MMSE)和视频~多导睡眠图(Video-PSG)监测。结果(1)睡眠结构分析:与对照组相比,DLB组总睡眠间期时间(SPT)减少,差异具有统计学意义(P〈0.05);总睡眠时间(TST)减少、睡眠效率(SE)下降、总醒觉时间(TWT)、入睡后清醒时间(WASO)增多、1期睡眠时间(TS1)、2期睡眠时间(TS2)、NREM睡眠时间(TNREMS)和REM睡眠时间(TREMS)均明显减少,差异具有统计学意义(P〈0.01);(2)睡眠呼吸事件分析:DLB组与对照组相比,各项指标差异均无统计学意义(P〉0.05);(3)其他睡眠事件分析:与对照组相比,DLB组睡眠期周期性肢体运动次数(PLMS)、快动眼睡眠行为异常(RBD)明显增多,差异具有统计学意义(P〈0.01)。结论DLB患者存在睡眠结构紊乱,睡眠异常行为亦很常见。视频-多导睡眠图对于研究DLB患者的睡眠障碍很有帮助。

关 键 词:路易体痴呆  视频-多导睡眠图  睡眠结构  快动眼睡眠行为异常

Analysis of Video-- Polysomnography in dementia with Lewy bodies
Institution:PENG Quan, S HI Hai-shan, HOU Le, et al. Department of Neuroscience, Dong Hua Hospital, Guangzhou Medical College, Dong- guan 523110, China
Abstract:Objective To investigate the sleep architecture in dementia with Lewy bodies (DLB). Methods Twenty--eight cases of DLB and 28 cases of normal control were included. All patients re- ceived Mini- mental state examination (MMSE) and video- polysomnographic (PSG) test. Results (1)Sleep architecture analysis: in DLB group, compared with normal control group, the sleep period time (SPT) reduced (P 〈 0.05) ; total sleep time (TST) and sleep efficiency (SE)decreased; totM wake time (TWT) and wake after sleep onset (WASO) increase; 1NREM sleep (TS1), 2NREM sleep (TS2), total NREM sleep (TNREMS) and REM sleep (TREMS) time were significantly decreased (P 〈 0.01). (2) Sleep apnea analysis : no statistical difference was observed (P 〉 0.05). (3) Periodic limb movement disorder (PLMS)and REM sleep behavior disorder (RBD)were more frequent in DLB group. Conclusions DLB patients have a wide range of sleep disorders. Video-- PSG is useful to investi- gate disrupted sleep in DLB.
Keywords:Dementia with Lewy bodies  Video--Polysomnography  REM sleep behavior dis- order
本文献已被 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号