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宫颈糜烂聚焦超声治疗后宫颈VEGF表达及临床指征的变化
引用本文:杜天竹,苑春丽,陈衡,罗新,黄晓慧,王菊凤. 宫颈糜烂聚焦超声治疗后宫颈VEGF表达及临床指征的变化[J]. 中国热带医学, 2009, 9(2): 308-309,382
作者姓名:杜天竹  苑春丽  陈衡  罗新  黄晓慧  王菊凤
作者单位:1. 广东医学院附属人民医院妇产科,广东深圳,518033
2. 岩林大学第一附属医院妇产科,吉林长春,130041
3. 暨南大学第一附属医院妇产科,广东,广州,510630
基金项目:深圳市科技局科研基金资助(编号:2007062)
摘    要:
目的探讨聚焦超声对糜烂面积、阴道流液时间及创面血管生成的影响。方法选择60例宫颈糜烂患者,随机分为聚焦超声组和微波组2组,观察糜烂面积、阴道流液时间,检测治疗前、治疗后1周、2周、3周、4周宫颈渗液VEGF的浓度。结果两组在糜烂面积均较治疗前减少,但减少幅度分别为(37.18+17.68)%、(34.72+11.83)%,组间比较差异无统计学意义(P>0.05)。超声组VEGF浓度在1周达峰,微波组在2周达峰,分别为(1664±363.5)pg/ml、(1073±378.4)pg/ml;超声组阴道流液时间(13.9±4.2)a,微波组(24.2±6.7)d,差异有统计学意义(P〈0.05;P〈0.01)。结论聚焦超声对中、重度以上的再治疗者单纯评价宫颈糜烂面积的减少并无明显优势,但能缩短阴道流液时间,可能与宫颈局部渗液VEGF浓度达峰时间更早有关。

关 键 词:宫颈糜烂  聚焦超声(HIFU)  血管内皮生长因子(VEGF)

The effect of focused ultrasound on vaginal liquid and expression of VEGF in cervical erosion patients.
DU Tian-zhu,YUAN Chun-li,CHEN Heng,et al.. The effect of focused ultrasound on vaginal liquid and expression of VEGF in cervical erosion patients.[J]. China Tropical Medicine, 2009, 9(2): 308-309,382
Authors:DU Tian-zhu  YUAN Chun-li  CHEN Heng  et al.
Affiliation:1.Futian Hospital Affliated to Guangdong Medical College;Shenzhen;518033;Guangdong;P.R.China
Abstract:
Objective To explore the effect of focuse ultrasound in the treatment of cervical erosion.The erosion area,interval of vaginal liquid and angiogenesis of raw surface of cervix were oberserved.Methods 60 cases of patients were devided into two groups.HIFU group and microwave group.Microwave group was the control group.The erosion area and interval of vaginal liquid were caculated.The concentration of VEGF on surface of cervix was detected.Results The erosion area in both groups were reduced(P>0.05).The reduc...
Keywords:Cervical erosion  HIFU  VEGF  
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