DETECTION OF HBsAg IN THE PANCREAS |
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Authors: | Makoto Yoshimura Isamu Sakurai Toshihiko Shimoda Kenji Abe Tadao Okano Toshio Shikata |
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Affiliation: | The Second Department of Pathology, Nihon University School of Medicine, Tokyo;*The First Department of Pathology, Nihon University School of Medicine, Tokyo |
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Abstract: | Hepatitis B surface antigen (HBsAg) has been reported to be present in other organs than the liver.3,9 So far as our knowledge is concerned, however, any report of cases dealing with pancreatic diseases induced by hepatitis B virus (HBV) has not been described in the English and Japanese literature. We report an autopsy case with a pancreatic lesion characterized by damage of both exocrine and endocrine epithelial cells with inflammatory response, which were immunohistochemically found to be positive for HBsAg, and electron-microscopically to possess core-like particles In the nucleus and cytoplasm. |
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