自由基清除剂与亚低温结合治疗急性脑梗死的临床探讨

目的：探讨自由基清除剂与亚低温结合治疗急性脑梗死的临床价值。方法选取本院2012年6月~2013年6月之间收治的100例急性脑梗死患者为研究对象，随机将其分为对照组和实验组，两组患者均接受常规基础性治疗，实验组在此基础上接受自由基清除剂，依达拉奉注射液联合亚低温治疗，回顾分析两组患者的临床疗效。结果实验组患者临床治疗后血糖、血乳酸、并发症发生率、神经功能缺损评分和治疗总有效率均明显优于对照组，差异有统计学意义（P〈0.05）。结论自由基清除剂联合亚低温治疗急性脑梗死，具有较为理想的临床疗效，因而推广和应用价值较高。

Clinical observation on correlation of serum level of HbA1c and GRACE risk score in patients with non-ST segment elevation acute coronary syndrome and type 2 diabetes

Objective To investigate correlation of serum level of HbA1c and GRACE risk score in patients with non-ST segment elevation acute coronary syndrome （NSTE-ACS） and type 2 diabetes. Methods All of 134 patients undergoing coronary angiography（CAG）, 67 patients were diagnosed with type 2 diabetes and NSTE-ACS, the other 67 patients with NSTE-ACS cases were served as control. The serum level of HbA1c was measured in peripheral venous blood by in all the patients, and the GRACE risk score were assessed in patients with type 2 diabetes. The serum level of HbA1c and GRACE risk score were analyzed by Spearman rank correlation. Results The serum level of HbA1c was significantly higher in patients with Type 2 diabetes and NSTE-ACS than the control （all P〈0.01）. The serum level of HbA1c in patients with NSTE-ACS were positively correlated with GRACE risk score （r=0.503, P=0.001）. Conclusion The serum level of HbA1c has a good consistency with GRACE risk score in NSTE-ACS patients with type 2 diabetes.