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| NP与MVP方案治疗非小细胞肺癌的临床观察 | |
| 引用本文： | 王志海,纪明. NP与MVP方案治疗非小细胞肺癌的临床观察[J]. 现代医药卫生, 2002, 18(4): 265-266 |
| 作者姓名： | 王志海 纪明 |
| 作者单位： | 青岛医学院第二附属医院,266042 |
| 摘 要： | 目的：观察诺维本（NVB）＋顺铂（DDP）（NP方案）与丝裂霉素（MMC）、西艾克（VDS）加顺铂（MVP方案）治疗晚期非小细胞肺癌（NSCLC）的临床疗效和不良反应。方法：采用NP与MVP两方案分别治疗晚期NSCLC 32例。结果：NP组总有效为43．8％，中位生存期7．7个月，MVP组总有效34．4％，中位生存期9．6个月，NP方案优于MVP方案，但差异无显著性（P＞0．05），两组剂量限制毒性均为骨髓抑制。结论：NP与INP方案是治疗晚期NSCLC的有效方案，经积极处理不良反应可以耐受。NP方案可作为首选方案。 |
| 关 键 词： | 非小细胞肺癌 临床观察 NP方案 MVP方案 联合化疗 |
| 文章编号： | 1009-5519(2002)04-0265-02 |
Clinical observation of NP and MVP combined chemotherapy for treating advanced non-small cell lung carcinoma. |
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| Wang Zhihai,Ji Ming. Clinical observation of NP and MVP combined chemotherapy for treating advanced non-small cell lung carcinoma.[J]. JOURNAL OF MODERN MEDICINE & HEALTH, 2002, 18(4): 265-266 | |
| Authors: | Wang Zhihai Ji Ming |
| Affiliation: | Wang Zhihai,Ji Ming.The Second Affiliated Hospital of Qingdao Medical college,Shandong 261011 |
| Abstract: | Objective:To observe the therapeutic effect and toxic side-effects of the combined chemotherapy with navelbine and cisplatin(NP regimen) and with micomycin plus vindesine and cisplatin(MVP regimen) in the treatment of advanced non-small cell lung carcinoma.Methods:Thirty-two patients received NP combied chemotherapy and thirty-two patients reveived MVP combied chemotherapy.Results:The overall response rate was 43.8% in the NP group and 34.4% in the MVP group.The median survival period was 7.7 months and 9.6 months respectively.NP regimen is better than MVP regimen in efficacy,but not dramatically different.Conclusion:This study shows that NP and MVP are active and tolerable regimens for trealment of advanced non-small cell lung carcinoma. |
| Keywords: | NP regimen MVP regimen Advanced non-small cell lung carcinoma Combined chemotherapy |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |