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| 运动病的中枢及外周递质能机制探讨 | |
| 引用本文： | 沈勤 吴扬. 运动病的中枢及外周递质能机制探讨[J]. 航天医学与医学工程, 1997, 10(2): 123-125 |
| 作者姓名： | 沈勤 吴扬 |
| 作者单位： | 南通医学院航海医学研究所 |
| 摘 要： | 采用绕垂直轴交替加速，减速旋转刺激诱发大鼠运动病的模型，测定了大鼠间脑和延桥脑内去甲肾上腺素，紧上腺素和５－羟色胺的含量，以及脑内乙酰胆碱酯酶的活性变化。同时测定了外周血液中乙酰胆碱，ＮＡ和Ａ的含量及红血球ＡｃｈＥ活性的变化。 |
| 关 键 词： | 运动病 神经递质 去甲肾上腺素 旋转实验 |
A Study on Central and Peripheral Nerve Transmitter Mechanism of Motion Sickness. |
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| SHEN Qin,WU Yang,NI Zhengxin,LI Bingyuan.. A Study on Central and Peripheral Nerve Transmitter Mechanism of Motion Sickness.[J]. Space Medicine & Medical Engineering, 1997, 10(2): 123-125 | |
| Authors: | SHEN Qin WU Yang NI Zhengxin LI Bingyuan. |
| Affiliation: | Institute of Navigation Medicine, Nantong Medical College, China. |
| Abstract: | Model of motion sickness(MS) was induced in rats by accelerating and decelerating vertical rotation for 60 min. The contents of Ach,NA,A and 5-HTand the activity of AchE in brain and blood of rats were examined after 60 min of rotation.The results showed:NA contents and AchE activity decreased significantly while A and 5-HT increased in rat's brain.Levels of Ach,NA and A in blood were increased.The results suggested that MS may be related to the imbalance of transmitters in the central nervous system resulting in the reduction of central arousal,and the imbalance between sympathetic and parasympathetic nerves. |
| Keywords: | motion sickness neuro transmitters acethylcholine norepinephrine rotation tests |
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