肝病血瘀证临床病理学特点和肝功能变化

肝脏病理组织学检查提示血瘀证组的碎屑坏死,桥形坏死,界板破坏,嗜酸性变等组织学改变明显高于非瘀血证组(P<0.01)。且肝功能的损害与血瘀证呈正相关。

Characteristics of Clinical Pathology and Changes of Liver Function in Blood Stasis Syndrome of Liver Disease

The experimental study on 30 patients of the Blood Stasis Syndrome of liver diseases wasdiscussed in this paper. Two characteristics were found. One was the pathological feature whichmanifested as follows; (1) Diagnosis: the Blood Stasis Syndrome of liver disease was mainlydiagnosed in the chronic active hepatitis and the early stage of cirrhosis of liver,while that ofnon-Blood Stasis was mainly observed in the chronic persistent hepatitis (P<0.01): (2) Pathologicalchange: The histological changes such as piecemeal necrosis, bridging necrosis. the destruction oflimiting plate, eosinophilic change, etc. It was more obvious in the Blood Stasis group than that withnon-Blood Stasis Syndrome (P<0.01), (3) The manifestation of Blood Stasis Syndrome was not inparallel with the severity of the liver disease. The another characteristic was the changes of liverfunction, which expressed more markedly in the Blood Stasis group with higher level of SGPT, lowerratio of A/G and increased globulin, they were more obvious than that in non-Blood Stasis group(P<0.01).