成都市孕妇及新生儿弓形虫感染的调查研究

调查成都市孕妇及其新生儿弓形虫感染各１２１１名。调查方法包括病史、体检和血清学检查。调查结果显示，孕妇和新生儿弓形虫ＩｇＧ抗体阳性率分别为３９．１４％和３２．１２％，ＩｇＭ抗体阳性率分别为４．２１％和０．９９％，成都地区弓形虫感染率较北方地区为高，新生儿先天性弓形虫感染与先天畸形间可能有一定关系（Ｐ＜０．０５，ＯＲ＝６．３２）。

The Prevalence of Toxoplasma Infection among Pregnant Women and Their newborn Infants in Chengdu

urpose of the study was to determine the prevalence of toxoplasma infection among the pregnant womenarid their newborn infants in Chengdu and to identify risk factors of acquiring toxomlasma infection. The Masternal and Child Health Hospital was elected by random claster sampling method in the study.Each pregnant women admitted to the above hospital consecutively and her surviving newborn at birth wereincluded in this survey.History,physical examination and blood specimens were obtained from 1 211 pairs ofmother-newborns. ELISA was used to detect toxoplasma IgG and IgM antibodies. Results revealed that sera prevalence of toxoplasma IgG antibodies and IgM antibodies of pregnant wo-men were 39.14% and 4.21% respectively.Seraprevalence of toxoplasma IgM antibodies of newborn infants was 1.07%. Congenital malformation of newborn infants may be associated with congenital toxomlasma infec-tion(P<0.05,OR=6.32).