| 我国人群和动物芽囊原虫感染研究进展 |
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| 引用本文： | 宁超群,艾琳,胡主花,陈军虎,田利光.我国人群和动物芽囊原虫感染研究进展[J].中国血吸虫病防治杂志,2021,33(1):95-101. |
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| 作者姓名： | 宁超群 艾琳 胡主花 陈军虎 田利光 |
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| 作者单位： | 1中国疾病预防控制中心寄生虫病预防控制所、WHO热带病合作中心、科技部国家级热带病国际联合研究中心、国家卫生健康委员会寄生虫病原与媒介生物学重点实验室（上海 200025）；2江西省南昌市疾病预防控制中心 |
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| 基金项目： | 国家自然科学基金(81473022);上海市科学技术委员会项目(18490741100);江西省卫生计生委科技计划(20186023)。 |
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| 摘 要： | 囊原虫（Blastocystis）是一种可寄生于人类和多种动物的单细胞、厌氧性肠道原虫，在全球广泛分布。芽囊原虫感染在我国健康人群、儿童、学生、门诊及住院患者、腹泻等人群中均有报道，免疫力低下人群感染率较高，广西和云南地区人群感染率相对较高。根据小亚基核糖体RNA（small?subunit ribosomal RNA，SSU rRNA）基因序列差异，芽囊原虫分为17种亚型（ST1～ST17），其中ST1～ST9、ST12亚型可感染人和动物，ST10～ST17亚型仅感染动物。我国人群芽囊原虫基因亚型以ST1～ST3为主，并存在ST1和ST3、ST1和ST2、ST2和ST3等混合基因亚型感染。本文就我国人群和不同动物感染芽囊原虫的流行病学、基因分型进行综述。
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| 关 键 词： | 芽囊原虫 流行特征 基因亚型 小亚基核糖体RNA 中国 |
Progress of researches on Blastocystis infections in humans and animals in China |
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| NING Chao-Qun,AI Lin,HU Zhu-Hua,CHEN Jun-Hu,TIAN Li-Guang.Progress of researches on Blastocystis infections in humans and animals in China[J].Chinese Journal of Schistosomiasis Control,2021,33(1):95-101. |
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| Authors: | NING Chao-Qun AI Lin HU Zhu-Hua CHEN Jun-Hu TIAN Li-Guang |
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| Institution: | 1 National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Key Laboratory of Parasite and Vector Biology, National Health Commission, Shanghai 200025, China；2 Nanchang Center for Disease Control and Prevention, Jiangxi Province, China |
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| Abstract: | Blastocystis is a unicellular,anaerobic,intestinal protozoan that infects humans and a variety of animals,which is widely prevalent across the world-Blastocystis infections have been detected in healthy populations,children,students,outpatients and inpatients,as well as diarrhea patients in China.High prevalence of Blastocystis infections has been reported in immunocompromised patients,and relatively high prevalence was seen in individuals living in Guangxi and Yunnan regions.Based on the small subunit ribosomal RNA(SSU rRNA)gene sequence,a total of 17 subtypes(ST1 to ST17)of Blastocystis have been characterized until now,among which ST1 to ST9 and ST12 infect humans and animals,and ST10 to ST 17 only infect animals.In China,ST1 to ST3 are predominant human Blastocystis subtypes,and ST1/ST3,ST1/ST2 and ST2/ST3 mixed infections have been also identified.This review mainly describes the epidemiology and genotypes of Blastocystis in humans and animals in China. |
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| Keywords: | Blastocystis Epidemiological feature Subtype Small-subunit ribosomal RNA China |
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