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2型糖尿病对小鼠下颌骨骨再生及辅助性T细胞17、调节性T细胞相关因子表达的影响
引用本文:王亚楠,吴旋,贾婷婷,冯瑶,刘世岳,徐欣,张东姣.2型糖尿病对小鼠下颌骨骨再生及辅助性T细胞17、调节性T细胞相关因子表达的影响[J].华西口腔医学杂志,2021,38(6):642-650.
作者姓名:王亚楠  吴旋  贾婷婷  冯瑶  刘世岳  徐欣  张东姣
作者单位:1.山东大学齐鲁医学院口腔医学院·口腔医院种植科 山东省口腔组织再生重点实验室 山东省口腔生物材料与组织再生工程实验室,济南 2500122.宁波口腔医院月湖分院种植科,宁波 3150003.山东大学齐鲁医学院口腔医学院·口腔医院牙周科 山东省口腔组织再生重点实验室 山东省口腔生物材料与组织再生工程实验室,济南 250012
基金项目:河北省医学科学研究课题计划(20190097)
摘    要:目的观察2型糖尿病对小鼠下颌骨骨再生以及辅助性T细胞17(Th17)、调节性T细胞(Treg)相关因子表达的影响。

关 键 词:2型糖尿病  骨再生  辅助性T细胞17  调节性T细胞  蛋白酪氨酸磷酸酶非受体型2  
收稿时间:2020-02-06
修稿时间:2020-09-07

Finite element analysis of the comprehensive impact of scar and maxillary expansion combined with protraction on the development of maxilla with cleft lip and palate after repair operation
Huang Wei,Li Yinghui,Guo Kaili,Zhou Yongchuan,Li Xiangjun.Finite element analysis of the comprehensive impact of scar and maxillary expansion combined with protraction on the development of maxilla with cleft lip and palate after repair operation[J].West China Journal of Stomatology,2021,38(6):642-650.
Authors:Huang Wei  Li Yinghui  Guo Kaili  Zhou Yongchuan  Li Xiangjun
Abstract:Objective To study the comprehensive impact of scar and maxillary expansion combined with protraction on the development of maxilla with cleft lip and palate after repair operation. Methods In the original finite element model of the maxilla with cleft palate, a finite element model of the maxilla with cleft lip and palate was established by using Boolean operation in ANSYS. Scar force after cleft lip and palate repair and maxillary expansion force combined with protraction were added simultaneously to process the stress analysis. Results Maxillary deformation occurred in the three-dimensional direction. The comparison of displacements was as follows: X-axis>Z-axis>Y-axis. Conclusion Maxillary growth is significantly inhibited in the three-dimensional direction under the comprehensive impact of scar and maxillary expansion combined with protraction after repair operation, especially transverse and sagittal growth.
Keywords:cleft lip and palate  scar  orthodontic treatment  maxillary growth  three-dimensional finite element  
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