小柴胡汤加味联合经鼻肠梗阻导管对粘连性肠梗阻治疗效果

目的:对小柴胡汤加味联合经鼻肠梗阻导管治疗粘连性肠梗阻的效果行回顾性分析。方法:按纳入标准收集湖南中医药大学第一附属医院普外微创科于2018年4月至2019年4月期间符合粘连性肠梗阻诊断的患者50例。随机分为2组,对照组(25例)和实验组(25例)。对照组行经鼻肠梗阻导管置入术治疗,术后予以常规治疗,实验组在常规治疗的基础上给予了小柴胡汤加味方治疗。2组均3天复查一次相关实验室指标。比较两组排气排便恢复时间、开始进食时间、导管的拔除时间、住院时间等指标,并比较两组患者炎性指标变化以及治疗结果。结果:对照组患者平均的排气排便恢复时间、腹痛腹胀消失时间、进食时间、气液平消失时间、导管拔除时间、平均住院时间普遍长于实验组;实验组患者治疗后白细胞(WBC)计数、C反应蛋白(CRP)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)等炎性指标的水平较对照组明显降低;实验组的总有效率高于对照组。结论:小柴胡汤加味联合经鼻肠梗阻导管对治疗粘连性肠梗阻比单纯使用经鼻肠梗阻导管治疗效果好。

Therapeutic Effect of Xiaochaihu Decoction Plus Combined with Transnasal Obstruction Catheter on Adhesive Intestinal Obstruction

Objective:Retrospectively analyzed the effect of Xiaochaihu decoction combined with transnasal intestinal obstruction catheter in the treatment of adhesive intestinal obstruction.Methods:According to the inclusion criteria,50 patients who met the diagnosis of adhesive intestinal obstruction from April 2018 to April 2019 in the Department of General Minimal Invasion of the First Affiliated Hospital of Hunan University of Traditional Chinese Medicine were collected.Randomly divided into 2 groups,control group(25 cases)and experimental group(25 cases).The control group underwent transnasal intestinal obstruction catheter insertion and received routine treatment after operation.The experimental group was given Xiaochaihutang Jiaweifang treatment on the basis of conventional treatment.Both groups reviewed the relevant laboratory indicators once every 3 days.The indexes of recovery time,time to start eating,time of catheter removal,hospitalization time and other indicators were compared between the two groups,and the changes of inflammatory indexes and treatment results of the two groups were compared.Results:The average recovery time of exhaustion and defecation,the disappearance time of abdominal pain and abdominal distension,the time of eating,the disappearance time of gas and liquid level,the time of catheter removal,and the average hospitalization time of the control group were generally longer than those of the experimental group;The levels of inflammatory indicators such as C-reactive protein(CRP),interleukin-6(IL-6),and interleukin-8(IL-8)were significantly lower than those of the control group;the total effective rate of the experimental group was higher than that of the control group.Conclusion:Xiaochaihu decoction combined with transnasal-intestinal obstruction catheter is better for treating adhesive intestinal obstruction than transnasal-intestinal obstruction catheter alone.