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| 严重少精子症和无精子症患者染色体核型分析 | |
| 引用本文： | 张洲,师娟子,周寒鹰,强荣. 严重少精子症和无精子症患者染色体核型分析[J]. 甘肃医药, 2009, 28(1) |
| 作者姓名： | 张洲 师娟子 周寒鹰 强荣 |
| 作者单位： | 西安交通大学医学院,陕西西安,710061;陕西省妇幼保健院,陕西西安,710061 |
| 基金项目： | 陕西省科技厅资助项目[2007k14-02(1)] |
| 摘 要： | 目的：探讨男性严重少精子症和无精子症与染色体异常的关系。方法：对364例严重少精子症和无精子症患者进行外周血淋巴细胞培养，G显带染色体核型分析。结果：严重少精子症和元精子症异常染色体检出率分别为6．29％（9／143）、11．76％（26／221）。严重少精子症以染色体易位为主77．78％（7／9），无精子症以染色体数目畸变占大多数88．46％（23／26）。结论：染色体异常是导致严重少精子症和无精子症的重要原因之一，在卵胞浆内单精子显微注射治疗前进行染色体核型分析是必要的。 |
| 关 键 词： | 少精子症 无精子症 染色体核型 |
Chromosomal karyotypes analysis on patients with severe oligospermia and azoospermia |
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| ZHANG Zhou,SHI Juan-zi,ZHOU Han-ying,QIANG rong .Xi''an Jiaotong university school of medicine,Xian China,. Maternal , child health hospital of Shaanxi province,Xian China. Chromosomal karyotypes analysis on patients with severe oligospermia and azoospermia[J]. , 2009, 28(1) | |
| Authors: | ZHANG Zhou SHI Juan-zi ZHOU Han-ying QIANG rong .Xi''an Jiaotong university school of medicine Xian China . Maternal child health hospital of Shaanxi province Xian China |
| Affiliation: | ZHANG Zhou1,2,SHI Juan-zi2,ZHOU Han-ying2,QIANG rong2 1.Xi'an Jiaotong university school of medicine,Xian 710061 China,2. Maternal and child health hospital of Shaanxi province,Xian 710003 China |
| Abstract: | Objective:To study the relation between severe oligospermia, azoospermia and abnormal chromosome karyotypes. Methods: The periphery blood lymphocyte was cultured and the G-banding chromosome was analyzed on 394 male patients with the severe oligospermia and azoospermia.Results: The incidence of abnormal chromosome karyotype was 6.29% or 9/143 in patients with severe oligospermia by the G-banding, which account for 77.78% or 7/9 in chromosome translocation. The incidence of abnormal chromosome karyotype was ... |
| Keywords: | Oligospermia Azoospermia Chromosomal karyotype |
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