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Lithium increases slow wave sleep: possible mediation by brain 5-HT2 receptors? |
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| Authors: | K. J. Friston A. L. Sharpley R. A. Solomon P. J. Cowen |
| Affiliation: | (1) MRC Unit of Clinical Pharmacology and University Department of Psychiatry, Research Unit, Littlemore Hospital, OX4 4XN Oxford, UK |
| Abstract: | The effect of lithium on slow wave sleep (SWS) was studied in ten normal male volunteers using home based cassette sleep recording and automatic sleep stage analysis. Lithium increased SWS, an effect consisten with a reduction in brain 5-HT2 receptor function. |
| Keywords: | Lithium Slow wave sleep 5-HT receptors Cassette sleep recording Automatic sleep stage analysis |
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