乙型肝炎危险因素病例对照研究

目的：了解湖州市乙肝病毒传播的主要危险因素。为制定防制对策提供科学依据。方法：以湖州市2006年病毒性肝炎血清流行病学调查中乙肝表面抗原阳性者为研究对象。采用1：2病例对照研究。结果：单因素分析显示乙肝感染的危险因素有家庭成员有乙肝、周围接触者有乙肝、共用牙刷、共用剃须刀、美容院创伤性治疗共5项;多因素分析显示家庭成员中有乙肝患者、美容院创伤性治疗及输血是目前湖州市乙肝感染的主要危险因素。结论：湖州市乙肝感染的危险因素还普遍存在，应加强乙肝防治知识的宣传教育。提高群众防范乙肝感染的意识和能力，进一步降低乙肝感染率。

A case-control study on risk factors of Hepatitis B

Objective To explore major risk factors of hepatitis B in Huzhou city and to provide a scientific basis for effective prevention.Method A one-to-two matched case control study was conducted including the people with HBsAg positive from the seroepidemiological investigation of viral hepatitis in the region of Huzhou in 2006.Results Single factor analysis showed that significant factors were family member with hepatitis B,people contacted with hepatitis B,toothbrush shared,razor shared,traumatic treatment in beauty salons.Analyzed by multiple conditional logistic regression,factors that finally entered the model were family member with hepatitis B,traumatic treatment in beauty salons,transfusion.Conclusions Risk factors of hepatitis B were prevalent in Huzhou.It was important to ensure that vaccination of Hepatitis B be used widely and public health education be carried out so as to reduce infection rate of Hepatitis B.