| 磷酸奥司他韦二日疗程治疗流行性感冒样病例的临床研究 |
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| 引用本文： | 张洪波,杨勤兵,朱宇清. 磷酸奥司他韦二日疗程治疗流行性感冒样病例的临床研究[J]. 中华全科医师杂志, 2009, 8(5): 342-343. DOI: 10.3760/cma.j.issn.1671-7368.2009.05.019 |
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| 作者姓名： | 张洪波 杨勤兵 朱宇清 |
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| 作者单位： | 1. 卫生部中日友好医院急诊科,北京,100029
2. 卫生部中日友好医院临床营养部,北京,100029 |
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| 摘 要： | 2005年11月至2007年3月,把86例流行性感冒（简称流感）样病例随机数字表法分为试验组（42例）和对照组（44例）,均服用磷酸奥司他韦75mg,每日2次,试验组疗程2d,对照组疗程5d,对比两组的疗效及所需费用。试验组和对照组平均退热时间分别为（56±14）h和（54±13）h（P=0．623）;恢复到发病前状态所需时间分别为（9．2±2．1）d和（8．8±1．8）d（P=0．487）;治疗费用分别为（193±38）元和（382±61）元（P=0．016）。提示磷酸奥司他韦两日疗程与五日疗程治疗流感样病例具有同等疗效,而费用低。
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| 关 键 词： | 酶抑制剂 流感 人 |
A randomized controlled clinical trial on the two-days course of oseltamivir in treatment of influenzalike diseases |
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| ZHANG Hong-bo,YANG Qin-bing,ZHU Yu-qing. A randomized controlled clinical trial on the two-days course of oseltamivir in treatment of influenzalike diseases[J]. Chinese JOurnal of General Practitioners, 2009, 8(5): 342-343. DOI: 10.3760/cma.j.issn.1671-7368.2009.05.019 |
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| Authors: | ZHANG Hong-bo YANG Qin-bing ZHU Yu-qing |
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| Affiliation: | .( Department of Emergency, Sino- Japanese Friendship Hospital, Beijing 100029, China) |
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| Abstract: | Eighty six patients with influenza-like diseases were randomly assigned to trial group (n=42,oseltamivir 75 mg,twice daily for 2 days)and control group(n=44,osehamivir 75 mg,twice daily for 5 days).The results showed that there Was no statistical difierence in the duration of fever between trial groups[(56±14)h]and control group[(54±13)h,P=0.623],the cost of the trial group[(193±38)yuan]Was 189 yuan less than that in the control group[(382±61)yuan,P=0.016].It is suggested that the efficacy of two-day course of oseltamivir is the same as that of five-day course in tlle treatment for influenza-like diseases,but with lower cost. |
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| Keywords: | Enzyme inhibitirs Influenza,human |
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