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| 长效避孕栓剂对家兔的抗生育作用 | |
| 引用本文： | 侯庆昌 陈绮. 长效避孕栓剂对家兔的抗生育作用[J]. 中国计划生育学杂志, 1999, 7(5): 198-199 |
| 作者姓名： | 侯庆昌 陈绮 |
| 作者单位： | 天津市计划生育研究所 300191(侯庆昌，陈绮，贺其刚，宁清)，天津市计划生育研究所 300191(沈丽琳) |
| 摘 要： | 目的和方法:是观察NP-9长效避孕栓(100mg/栓)于家兔阴道给药后15分钟和3.5小时的抗生育作用和连续7天给药的阴道刺激试验。结果:长效避孕栓无论在给药15分钟还是3.5小时交配避孕率均为100％。而生理盐水和赋型剂对照组避孕率分别为0％和40％。家兔阴道刺激试验结果表明:该栓剂阴道刺激炎症总分值为6.9,在可接受范围内。 |
| 关 键 词： | 长效NP-9栓 抗生育作用 阴道刺激 |
The Antifertiiity of NP-9 Long-Acting Suppository in the Rabbits. |
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| Hou Qingchang Chen Qi,He Qi-gang,et al.. The Antifertiiity of NP-9 Long-Acting Suppository in the Rabbits.[J]. Chinese Journal of Family Planning, 1999, 7(5): 198-199 | |
| Authors: | Hou Qingchang Chen Qi He Qi-gang et al. |
| Affiliation: | Hou Qingchang Chen Qi,He Qi-gang,et al. Tianjin Municipal Research Institute for Family Planning,Tianjin,300191. |
| Abstract: | The objective of the present study was to e-valuate the antifertility and vaginal irritation NP-9 long-acting contraceptive suppository administrated vaginally. During the study of antifertility twenty female rabbits were divided into group l(normal saline) , group 2(vehicle), group 3(drug 15min)and group 4(drug 3.5hr) randomly. The dosage was 100mg per suppository per individual. Our results showed that contraceptive rates of group 1 and group 2 were both 100%. The contraceptive rates in group 3 and group 4 were 0% and 40% , respectively. The results of vaginal irritation experiment indicated that total inflammation score of NP-9 long-acting suppository was 6.9 which was less than 8 and acceptalble. |
| Keywords: | NP-9 Long -acting suppository Antifer-tility Vaginal irritation |
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