Expression of androgen receptor and prostate-specific antigen in male breast carcinoma |
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Authors: | Noman?Kidwai,Yun?Gong,Xiaoping?Sun,Charuhas?G?Deshpande,Anjana?V?Yeldandi,M?Sambasiva?Rao,Sunil?Badve mailto:sbadve@iupui.edu" title=" sbadve@iupui.edu" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author |
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Affiliation: | (1) Northwestern University Medical School, Chicago, IL, USA;(2) Indiana University School of Medicine, Indianapolis, IN, USA; |
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Abstract: |
Background The androgen-regulated proteins prostate-specific antigen (PSA) and prostate-specific acid phosphatase (PSAP) are present in high concentrations in normal prostate and prostatic cancer and are considered to be tissue-specific to prostate. These markers are commonly used to diagnose metastatic prostate carcinoma at various sites including the male breast. However, expression of these two proteins in tumors arising in tissues regulated by androgens such as male breast carcinoma has not been thoroughly evaluated. |
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