| 丹参对肢体缺血再灌注所致肺损伤的保护作用 |
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| 引用本文： | 陈建常 王乐农. 丹参对肢体缺血再灌注所致肺损伤的保护作用[J]. 中国中西医结合外科杂志, 2000, 6(6): 412-414 |
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| 作者姓名： | 陈建常 王乐农 |
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| 作者单位： | 兰州军区乌鲁木齐总医院,乌鲁木齐 |
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| 摘 要： | 目的;通过动物实验方法观察丹参对肢体缺血再灌注所致肺损伤的保护作用。方法：１１０只Ｗｉｓｔａｒ大鼠随机分成正常对照,缺血３ｈ和缺血３ｈ用丹参３个组。实验组用于缺血、再灌注１、２、３和２４ｈ取材,光镜下对比观察和组织学评估。结果：肢体缺血和再灌注后,实验组肺泡隔增厚、水肿、毛细血管扩张、充血、大量多核白细胞浸润,贴壁,部分肺不张。用丹参组的病理改变明显轻于未用丹参组。结论：丹参能有效地减轻肢体缺血再灌注所致的肺损伤。
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| 关 键 词： | 丹参 中医药治疗 肺损伤 肢体缺血 再灌注损伤 |
Protective Effect of Radix Salvia Miltiorrhiza on Lung Injury after Lower Limb Ischemic Reperfusion |
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| Chen Jianchang,WangLenong,ShiZhenman,etal Departmentoforthopaedics,UlumqiGeneralHospitalofPLA,Lanzhou Command,Ulumqi. Protective Effect of Radix Salvia Miltiorrhiza on Lung Injury after Lower Limb Ischemic Reperfusion[J]. Chinese Journal of Surgery of Integrated Traditional and Western Medicine, 2000, 6(6): 412-414 |
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| Authors: | Chen Jianchang WangLenong ShiZhenman etal Departmentoforthopaedics UlumqiGeneralHospitalofPLA Lanzhou Command Ulumqi |
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| Abstract: | AnexperimentalstudytoobservetheprotectiveeffectofRadixSalviaMiltiorrhiza(RSM)onlunginjury afterlowerlimbischemicreperfusion .Methods :Wistarrats 110innumberweredividedintoacontrolgroup ,ischemia 3 -hourgroupandischemia 3hourgrouptreatedwithRSM .Thehistologicalassessmentoflungwasundertakenat0 ,1,2 , 3and 2 4hoursafterreperfusion .Results :Pulmonaryedema ,microvascularcongestion ,excessiveinfiltrationofpolymor phonuclearneutrophilandpartialpulmonarycollapsewerefoundinexperimentalgroupsat 0 ,1,2 ,3and 2 4hoursafter reperfusion .TherewasasignificantlesseningofthepulmonaryinjuryinthegrouptreatedwithRSM .Conclusion :Itis suggestedthatRSMcanalleviatethelunginjuryafterlowerlimbischemicreperfusioin . |
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| Keywords: | RadixSalviaMiltorrhiza limb ischemicreperfusion lunginjury |
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