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No evidence of Legionella infection in general practice patients presenting with acute respiratory infections in The Netherlands
Authors:B. M. W. Diederen  C. M. A. de Jong  I. Aarts  M. F. Peeters  A. B. van Gageldonk-Lafeber  B. Wilbrink   A. van der Zee
Affiliation:Laboratory of Medical Microbiology, St Elisabeth Hospital, Tilburg, The Netherlands. b.diederen@elisabeth.nl
Abstract:
The role of Legionella spp. in the aetiology of acute respiratory infections (ARIs) is largely unknown. In this case-control study, conducted in a general practitioner setting during 2000 and 2001, nose and throat samples from patients presenting with ARIs (n = 230) and controls (n = 200) were analysed for the presence of Legionella spp. by real-time PCR. Legionella DNA was not detected in any of the cases or controls. Thus, Legionella spp. do not seem to play a role in patients presenting with ARIs, nor were they present in patients who visited their general practitioner for complaints other than ARIs.
Keywords:Acute respiratory infections    general practice    Legionella spp.    real-time PCR    respiratory tract infection
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