Molecular characteristics of carbapenemase-producing Enterobacteriaceae in China from 2008 to 2011: Predominance of KPC-2 enzyme |
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| Authors: | Henan Li Jixia Zhang Yingmei Liu Rui Zheng Hongbin Chen Xiaojuan Wang Zhanwei Wang Bin Cao Hui Wang |
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| Affiliation: | 1. Department of Clinical Laboratory, Peking University People''s Hospital, Beijing, China;2. Department of Clinical Laboratory, Aviation General Hospital, Beijing, China;3. Department of Infectious Diseases and Clinical Microbiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China;4. Department of Clinical Laboratory, First People''s Hospital of Yunnan Province, Kunming, Yunnan, China |
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| Abstract: | ![]()
Among 228 carbapenem-nonsusceptible Enterobacteriaceae isolated in China, 65 were carbapenemase-producing Enterobacteriaceae (CPE). Among them, 41, 22, 1, and 1 produced KPC-2, IMP-4, IMP-8, and IMP-1, respectively. KPC-2-producing CPE showed higher resistance than IMP-4-producing ones. Furthermore, the first outbreak of ST11 KPC-2-producing Klebsiella pneumoniae in a Beijing second-degree hospital was identified. |
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| Keywords: | Carbapenemase-producing Enterobacteriaceae KPC-2 IMP-4 |
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