炎性细胞在各型突出椎间盘中出现率的比较以及与直腿抬高试验的相关性

目的研究炎性细胞在各型突出椎间盘中出现率以及与临床症状的相关性.方法使用碱性磷酸酶～抗碱性磷酸酶染色法和各种炎性细胞的单抗.免疫染色结果与临床资料进行比较.用卡方检验或F检验.结果205例标本,17%发现T细胞,17%发现活化T细胞,16%发现B细胞,37%发现巨噬细胞.在脱垂游离型中发现的各种炎性细胞是突出型中的2～3倍.25%(4/16)的突出型标本只见到巨噬细胞.双侧直腿抬高试验阴性与直腿抬高角度≤30°的病人相比较各种炎性细胞的出现情况,活化T细胞和巨噬细胞与直腿抬高角度≤30°有显著的相关性(CD68,P＜0.025;CD25,P＜0.04).双侧直腿抬高试验阳性与双侧阴性比较,四种炎性细胞与之都有显著的相关性(P=0.016;P=0.029).结论在直腿抬高试验阳性和脱垂游离型病人标本中炎性细胞最常见.直腿抬高试验与炎性细胞有一定的相关性,特别是双侧直腿抬高试验阳性与阴性相比较.双侧直腿抬高试验阳性与四种炎性细胞均有相关性,而直腿抬高角度≤30°与巨噬细胞也有相关性.表明炎性细胞可能与坐骨神经痛有关.

Comparation of rate of inflammatory cells occurrence in diversified disc herniation and relativity of in flammatory cells occurrence and straight leg raising experiment

Objective:To compare the occurrence of inflammatory cells in various subtypes of DH and to deter-mine the association between clinical data and inflammatory cell occurrence in a more extensive sample of DH.Methods:The alkaline phosphatase antialkaline phosphatase methos and monoclonal antibodies to inflammatory cells were used.Immunostaining results were compared with clinical data.Results:Of all the205cases,T cells were seen in17%,activated T cells in17%,B cells in16%,and macrophages in37%.Comparison between SLR bilaterally postitve and bilaterally negative showed associations for all four inflammatory cells.Conclusions:Inflam-matory cells are most commonly seen when SLR is positive and the DH types is sequestered.SLR bilaterally positive is associated with four types inflammatory cells.