北京地区患者沙眼衣原体、淋球菌及解脲脲原体感染分析

目的分析门急诊患者泌尿生殖道沙眼衣原体(CT)、淋病奈瑟菌(NG)及解脲脲原体(UU)感染情况。方法选取2014年1月至2019年6月北京大学第三医院诊治的23 847例门急诊就诊患者的CT、NG和UU荧光核酸恒温扩增检测结果及相应临床诊断信息进行回顾性分析。结果 23 847例患者中,22 953例男性患者CT、NG、UU的检出率分别为5.0%、2.0%与22.6%;894例女性患者CT、NG、UU的检出率分别为7.9%、1.9%与48.9%。女性患者CT、UU检出率均高于男性,差异具有统计学意义(P=0.000),而NG检出率差异无统计学意义(P=0.858)。按年龄段分层,各性别中CT、NG最高检出年龄段均为≤20岁年龄段。临床诊断明确的男性患者中,CT检出最高为附睾炎(27.4%)人群,NG检出率则以尿道炎患者(16.7%)最高,UU检出率最高为不育症患者(32.6%)。结论女性患者CT检出率高于男性,男性附睾炎患者应注意筛查CT、NG。

Infection of Chlamydia trachomatis,Neisseria gonorrhoeae and Ureaplasma urealyticum in patients in Beijing

Objective To analyze the prevalence of Chlamydia trachomatis(CT),Neisseria gonorrhoeae(NG)and Ureaplasma urealyticum(UU)in patients with suspected urogenital infections.Methods A retrospective analysis was performed to collect the clinical and laboratory data of 23847 patients who visited outpatient department and emergency department in our hospital from January 2014 to June 2019.The three pathogens were tested with simultaneous isothermal amplification assay in urine or secretion samples.Results The positive rates of CT,NG and UU were 5.0%,2.0%and 22.6%for 22953 male patients and 7.9%,1.9%and 48.9%for 894 female patients.The positive rates of CT and UU in female patients were higher than those in males(P=0.000),but there was no difference in the positive rate of NG(P=0.858).According to the age group,the highest detection ages of CT and NG in all genders are all≤20 years old group.Among the male patients with clear clinical diagnosis,the highest detection rate of the three pathogens were epididymitis group for CT(27.4%),urethritis group for NG(16.7%)and infertility group for UU(32.6%),respectively.Conclusions The positive rate of CT in female patients is higher than that in male patients,and CT and NG screening is recommended to male patients with epididymitis.