| 全身化疗联合腹腔化疗治疗晚期卵巢癌的临床观察 |
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| 引用本文： | 黄卫兵,朱敏,成美英. 全身化疗联合腹腔化疗治疗晚期卵巢癌的临床观察[J]. 肿瘤基础与临床, 2008, 21(6) |
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| 作者姓名： | 黄卫兵 朱敏 成美英 |
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| 作者单位： | 镇江市第一人民医院,江苏,镇江,212002;镇江市第一人民医院,江苏,镇江,212002;镇江市第一人民医院,江苏,镇江,212002 |
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| 摘 要： | 目的 观察全身化疗联合腹腔化疗对晚期卵巢癌的疗效及毒副反应.方法 24例卵巢癌,用紫杉醇135 mg/m2,卡铂400 mg/m2静滴,每4周重复1次,共化疗2个周期,顺铂60 mg,地塞米松10 mg腹腔化疗,每2周1次,进行2～3个周期,中位疾病进展时间(MTTP)9个月(5～12个月),无复发生存期5个月,观察每次化疗毒副反应及疗效.结果 24例中CR 12例、PR 7例,RR 79.2%,毒副反应为剂量限制性骨髓抑制、消化道反应.结论 全身化疗联合腹腔化疗对晚期卵巢癌有较好疗效.
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| 关 键 词： | 卵巢癌 紫杉醇 卡铂 顺铂 化疗 |
The Clinical Observation of Chemotherepy Combined with Intraperitoneal Chemotherepy in Advanced Ovarian Carcinoma |
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| Huang Weibing,Zhu Min,Cheng Meiying. The Clinical Observation of Chemotherepy Combined with Intraperitoneal Chemotherepy in Advanced Ovarian Carcinoma[J]. Journal of Basic and Clinical Oncology, 2008, 21(6) |
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| Authors: | Huang Weibing Zhu Min Cheng Meiying |
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| Affiliation: | Huang Weibing,Zhu Min,Cheng Meiying(The First People's Hospital of Zhenjiang,Zhenjiang 212002,China) |
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| Abstract: | Objective To evaluate the results and toxicity of chemotherapy combined with intraperitoneal chemotherapy in advanced ovarian carcinoma.Methods 24 cases with advanced ovarian carcinoma were treated with paclitaxel 135 mg/m2 and carboplatin 400 mg/m2 intravenous chemotherapy,cisplatin 60 mg and dexamethasone 10 mg intraperitoneal chemotherapy.Results 24 cases were eligible for evaluation,the overall response rate was 79.2%(12 complete response and 7 partial response),median TTP were 9 months(5-12 months).The... |
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| Keywords: | ovarian carcinoma paclitaxel carboplatin cisplatin chemotherapy |
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