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Functional Mapping of the Human Somatosensory Cortex with Echo-Planar MRI
Authors:Kuniyoshi Sakai  Eiju Watanabe  Yukari Onodera  Hiroyuki Itagaki  Etsuji Yamamoto  Hideaki Koizumi  Yasushi Miyashita
Abstract:The somatotopical organization of the human somatosensory cortex was analyzed with echo-planar imaging at 1.5 Tesla, utilizing deoxyhemoglobin as an endogenous contrast medium. Scrubbing stimulation at a frequency of 3 Hz was applied to one of three cutaneous areas: toes, fingertips, and tongue tip. Parasagittal echo-planar slices were obtained every 2 s. We found focal bands of increased signal intensity (4% on average) during the stimulation, with a rise time of 2–6 s. These activated bands were located on the contralateral postcentral gyrus. The cortical responses from the three stimulation sites were anatomically distinct and organized medially-to-laterally in the order of toes, fingertips, and tongue tip.
Keywords:functional MRI  echo-planar imaging  human brain mapping  somatosensory cortex
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