部分脾栓塞术后脾栓塞综合征119例临床分析

目的：探讨部分脾栓塞术（PSE）治疗肝硬化脾功能亢进发生脾栓塞综合征（SES）的发病机理及处理方法。方法：回顾性分析119例乙肝肝硬化合并脾脏肿大、脾功能亢进患者的临床资料。结果：手术均成功，随访6个月～2年，106例白细胞、血小板恢复正常或接近正常范围，有效率为89％；研究组及对照组中栓塞剂的使用、栓塞程度、术前肝功能分级对处理结果无显著性差异，对照组及研究组中-重度疼痛、中-高热发生率分别为80％、35％和88％、47％，有显著性差异，P〈0．01。结论：规范的术中、术后处理能有效地降低PSE综合症的发生及并减轻症状。

The 119 Cases Clinical Analysis of Splenic Embolization Syndrome after Partial Splenic Embolization

Objective: To explore the mechanism of splenic embolization syndrome (SES) of partial splenic embolization (PSE) and to study the treatment. Methods: The clinical data of 119 cases of cirrhosis with hypersplenism and hypersplenotrophy were analyzed retrospectively. Results:The procedure was successful in all 119 patients. The white blood cells and platelets were normal or close to normal in 106 of 119 (89%) cases in 6 months-2 years follow-up. The medium-severe pain and the medium-high fever of SES were 80% & 35% and 88% & 47% in conventional group and standard group respectively, P < 0.01. Conclusion: The standard therapy was more effective than the conventional therapy in controlling the SES.