| HUMAN UMBILICAL CORD BLOOD TRANSPLANTATION IN 4 CASES WITH ADVANCED SOLID TUMORS |
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| 引用本文： | 沈柏均,侯怀水,张洪泉,隋星卫,刘晓艳,丁欣荣,马秀峰,时庆,高宣. HUMAN UMBILICAL CORD BLOOD TRANSPLANTATION IN 4 CASES WITH ADVANCED SOLID TUMORS[J]. 山东大学学报(医学版), 1993, 0(1) |
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| 作者姓名： | 沈柏均 侯怀水 张洪泉 隋星卫 刘晓艳 丁欣荣 马秀峰 时庆 高宣 |
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| 作者单位： | Dept.of Pediatrics and Cryomedicine Laboratory the Affiliated Hospital of Shandong Medical University，Dept.of Pediatrics and Cryomedicine Laboratory，the Affiliated Hospital of Shandong Medical University，Dept.of Pediatrics and Cryomedicine Laboratory，the Affiliated Hospital of Shandong Medical University，Dept.of Pediatrics and Cryomedicine Laboratory，the Affiliated Hospital of Shandong Medical University，Dept.of Pediatrics and Cryomedicine Laboratory，the Affiliated Hospital of Shandong Medical University，Dept.of Pediatrics and Cryomedicine Laboratory，the Affiliated Hospital of Shandong Medical University，Dept.of Pediatrics and Cryomedicine Laboratory，the Affiliated Hospital of Shandong Medical University，Dept.of Pediatrics and Cryomedicine Laboratory，the Affiliated Hospital of Shandong Medical University，Dept.of Pediatrics and Cryomedicine Laboratory，the Affiliated Hospital of Shandong Medical University |
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| 摘 要： | ![]()
Four patients with solid tumors were treated by means of highdose chemotherapy and HLA-mismatched multi-cord blood transplantation.Ofthem,3 reached complete remission,1 got fair response with tolerant side-effects.No or a little graft-versus-host reaction(GVHR)were observed.Donor cellengraftments were documented in 2 patients by cytogenetic analysis and deter-mination of hemoglobin F of the peripheral blood.Recurrent diseases wereconfirmed clinically on day 210(4 year-old girl with liposarcoma)and day 90(11 year old boy with Non-Hodgkin′s Lymphoma).These results demonstratedthat HLA-mismatched multicord blood transfusion could rescue the marrowsuppression of patients treated with myeloablative chemotherapy with no or a littleGVHR,and suggested that muIticord blood stem cells might be engrafted in asingle patient without consideration of HLA-identical.Therefore,cord blood mayprovide a rich hematopoietic resources.Further studies are needed to confirmour observation.
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HUMAN UMBILICAL CORD BLOOD TRANSPLANTATION IN 4 CASES WITH ADVANCED SOLID TUMORS |
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| Shen Baijun,Hou Huaishui,Zhang Hongquan,Sui Xingwei,Liu Xiaoyan,Ding Xinrong,Ma Xiufeng,Shi Qing,Gao Xuan Dept.of Pediatrics and Cryomedicine Laboratory,the Affiliated Hospital of Shandong Medical University. HUMAN UMBILICAL CORD BLOOD TRANSPLANTATION IN 4 CASES WITH ADVANCED SOLID TUMORS[J]. Journal of Shandong University:Health Sciences, 1993, 0(1) |
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| Authors: | Shen Baijun Hou Huaishui Zhang Hongquan Sui Xingwei Liu Xiaoyan Ding Xinrong Ma Xiufeng Shi Qing Gao Xuan Dept.of Pediatrics Cryomedicine Laboratory the Affiliated Hospital of Shandong Medical University |
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| Abstract: | ![]()
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| Keywords: | Human Umbilical Cord Blood Transplantation Solid Tumors Children |
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