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冠心病患者左室舒张功能的改变和硝苯吡啶的作用
引用本文:杜昌林,胡昭明,高淑英. 冠心病患者左室舒张功能的改变和硝苯吡啶的作用[J]. 华中科技大学学报(医学版), 1992, 0(4)
作者姓名:杜昌林  胡昭明  高淑英
作者单位:同济医科大学附属同济医院内科(杜昌林,胡昭明),同济医科大学附属同济医院超声诊断室(高淑英)
摘    要:
采用脉冲多普勒超声心动图测定31例冠心病人和30例正常人的左室舒张功能,并观察冠心病人舌下含服硝苯毗啶10mg后多普勒指标的变化。结果表明,冠心病人左室舒张早期功能受损,但并非所有反映左室舒张早期功能的指标均异常,各单项指标的敏感性不高,应测量多项指标进行综合判断,值得选用的指标有PeakE、MeanE、Earea、EAV、IVRT、PeakA/PeakE、MeanA/MeanE和Aarea/Earea。硝苯吡啶可改善冠心病人的左室舒张早期功能。

关 键 词:冠状动脉疾病  左室舒张功能  硝苯吡啶  超声心动描记术  多普勒

Changes in the Left Ventricular Diastolic Function ofPatients with Coronary Artery Disease and theEffects of Nifedipine
Du Changlin,Hu Zhaoming,Gao Shuying. Changes in the Left Ventricular Diastolic Function ofPatients with Coronary Artery Disease and theEffects of Nifedipine[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 1992, 0(4)
Authors:Du Changlin  Hu Zhaoming  Gao Shuying
Affiliation:Du Changlin,Hu Zhaoming,Gao ShuyingDepartment of Internal Medicine,Tongji Hospital,Tongji Medical University,Wuhan
Abstract:
The left ventricular diastolic function (LVDF) of 31 patients with coronary artery disease (CAD) and 30 normal subjects were measured with pulsed Doppler echocardiography. The changes of Doppler indexes in CAD patients were observed after sublingual administration of nifedipine (10 mg), The results showed that the early LVDF in CAD patients was damaged, but not all indexes of early diastolic function were abnormal. The sensitivity of a single index was not high, so we should measure all the indexes and analyse the results synthetically. The valuable indexes are Peak E, Mean E, Earea, EAV, IVRT, Peak A/Peak E and Mean A/Mean E, A area/E area. Nifedipine can improve the early LVDF of CAD patients.
Keywords:coronary artery disease  left ventricular diastolic function  nifedipine  echocardiography   Doppler
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