单囊型成釉细胞瘤的临床病理特点及其与复发的关系

目的：探讨单囊型成釉细胞瘤的临床病理变化及其与患者预后的关系。方法：回顾分析33例单囊型成釉细胞瘤的临床和X线特点以及相关随访资料，并对照观察该型肿瘤的组织结构、生长方式以及肿瘤性上皮衬里的形态特征。结果：本组10－29岁为高发年龄，91％发生于下颌骨，累及上颌骨者仅3例；根据组织学特点，本组肿瘤被分为单纯囊型（I型，8例）、伴囊腔内瘤结节增殖（Ⅱ型10例）和伴囊内肿瘤浸润（Ⅲ型，15例），3种亚型，29例随访患者中有6例术后复发，手术与复发间隔4－11年不等。结论：综合分析随访和临床病理资料，提示肿瘤复发可能与其发生部位、术前临床诊断以及组织不分型有关。

Clinicopathological features of unicystic ameloblastoma with special reference to its recurrence

Objective To clarify the clinicopathological spectrum and biologic behavior of unicystic ameloblastomas (UA). Methods Retrospective analysis of 33 UA was undertaken to relate clinicopathological variables to recurrence. Results The clinical features of this series were in general agreement with that of the previous reports. UA tended to occur at an earlier age (mean 25 3 years), with a male predilection and predominant mandibular involvement (90 9%). Microscopically, the tumors demonstrated a generally monocystic growth pattern, with 8 being simple cystic, 10 comprising intraluminal nodules, and 15 exhibiting a conspicuous component of infiltrative tumor islands in the cyst capsule. Follow up of 29 patients revealed 6 recurrences with an average interval of 7 years. Recurrence also related to histologic subtypes of UA, with those invading the fibrous wall having a rate of 35 7% but others 6 7%. Conclusions Despite the fact that unicystic ameloblastoma may, in general, compare favorably with its solid or multicystic counterpart in terms of clinical behavior and response to treatment, the subsets of the maxillary lesions or tumors exhibiting mural invasion could have a high risk of recurrence.