电针刺激对胸膜炎大鼠白细胞游出的影响及其作用机制的研究

<正> 一系列的临床观察和实验研究证实,针刺可提高患病机体的防御能力,对炎症过程进行调整而抑制炎症的病损。临床观察发现,针刺能有效地治疗很多急、慢性炎症。实验研究亦表明,电针刺激可有效地抑制炎症的渗出和肉芽组织增生。但有关针刺对

EFFECTS OF ELECTRO-ACUPUNCTURE ON LEUKOCYTE MIGRATION AND STUDIES OF THE EFFECTIVE MECHANISM IN RATS OF PLEURISY

Electro-acupuncture could suppress the leukocyte migration to the inflam- matory focus in the rats of carrageenan-pleurisy.The result of analyses of stepped regression by micro-computer indicated that enhanced leukocyte chemo- taxis in inflammation is a main factor which effects leukocyte migation. Leukocyte chemotaxis is regulated by intracellular cAMP and cGMP levels. This paper demonstated that electro-acupuncture might inhibit leukocyte chemo- taxis,increase intracellular cAMP level which decreased during inflammation and decrease intracellular cGMP level which increased during inflammation. The effects of electro-acupuncture on cAMP and cGMP are probably substance basis inhibiting leukocyte chemotaxis,while showing the modulation of acu- puncture.