原发性闭角型青光眼的流行病学研究及分类现状

原发性闭角型青光眼是一种独立而复杂的疾病,目前国际上广泛采用的国际地域性和流行病眼科学组(ISGEO)分类系统,强调必须具有青光眼性视神经病变才能诊断为原发性闭角型青光眼,否则只能诊断为原发性前房角关闭.ISGEO分类系统与我国沿用至今的传统分类有一定差异,在某种程度上限制了与国际间的合作交流.因此,有必要就不同分类系统下原发性闭角型青光眼的流行病学调查结果、ISGEO分类系统的特点进行综述,旨在为推动我国闭角型青光眼的临床研究提供理论依据.

Epidemiology and classification of primary angle-closure glaucoma today

Primary angle-closure glaucoma (PACG) is an independent and complex disease.According to International Society Geographical & Epidemiological Ophthalmology (ISGEO) PACG is defined as primary angle closure (PAC) with glaucomatous neuropathy,whereas a diagnosis of PAC will be given to patients without a neuropathy.This classification is simple and very useful in survey.In contrast,conventional classification of PACG by Chinese Glaucoma Association is based on anatomical predisposition,such as peripheral iridocorneal apposition/adhesions,and functional sub-stages,which is more clinical usefulness.The difference of PACG classification system between Chinese Glaucoma Association and ISGEO appears to hinder the communication and cooperation between Chinese and intemational colleague.In this article,we attempted to review classifications and analyze the epidemiological characteristics of PACG under these two systems.It is obvious that the continuing effects to establish a rational and standardized classification system of PACG will greatly promote and benefit glaucoma research and clinical practice for both international and domestic ophthalmic community.