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Mycobacterium marinum arthritis
Authors:MDJeff A. Alloway   Major   USAF MC   Section of Rheumatology   Stephen M. Evangelisti   Major   USAF MC  Jeffrey S. Sartin   Major   USAF MC   Section of Infectious Disease
Abstract:
Mycobacterium marinum is an atypical acid-fast organism that is rarelyassociated with septic arthritis. Most often this is seen in patients with monarticular synovitis of the hands or wrists, especially in association with a history of periarticular trauma or exposure to marine environments. From tissue obtained by aspiration or synovectomy, Mycobacterium marinum can be identified by Ziehl-Nielson stain and has optimal growth in Lowenstein-Jenson medium. Therapy should consist of at least two anti mycobacterial agents for a minimum 6 months. Surgical debridement also may be beneficial. The clinician must have a high index of suspicion that exposure to Mycobacterium marinum has occurred so appropriate stains and cultures can be obtained and antimycobacterial therapy initiated.
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