心肌梗死患者非酒精性脂肪性肝病的发生率及危险因素分析

目的探讨心肌梗死患者非酒精性脂肪性肝病（non—alcoholicfattyliverdisease，NAFLD）的发病率和危险因素。方法对北京安贞医院634例诊断为心肌梗死的患者在入院期间行空腹肝胆超声检查，并分为NAFLD组和非NAFLD组，统计分析两组发病率和危险因素。结果心肌梗死患者NAFLD发生率为52．2％（331／634）。NAFLD组体重指数、血清丙氨酸转氨酶高于非NAFLD组，两组差异有统计学意义（P〈0．05）。NAFLD的发生率随着冠脉病变程度加重而增加（x2=7．275，P=0．03）。多因素logistic回归结果显示，体重指数和冠心病多支病变、左主干病变是NAFLD的独立危险因素。结论心肌梗死患者，尤其是体重超重、多支病变、左主干病变的患者NAFLD的发生率高。

Incidence and Risk Factors of Myocardial Infarction Complicated by Non-Alcoholic Fatty Liver Disease

Objective To investigate the incidence and risk factors of non-alcoholic fatty liver disease （NAFLD） in patients with myocardial infarction. Methods A total of 634 patients with myocardial infarction from Beijing Anz- hen Hospital were asked to take liver and gallbladder ultrasonography during hospitalization, and then divided into the NAFLD and non-NAFLD groups. The incidence and risk factors of the two groups were then analyzed. Results The in- cidence of NAFLD was 52.2% （331/634）. Both body mass index （BMI） and serum alanine aminotransferase of the NAFLD group were higher than those of non-NAFLD group, with significant difference （P〈0.05）. The incidence of NAFLD was positively increased following the severity of coronary diseases 0（2=7.275, P=0.03）. The result of multivariable logistic regression analysis showed BMI, multi-vessel lesions of coronary disease, and left main coronary artery lesion were the independent risk factors of NAFLD. Conclusion The myocardial infarction patients who are particularly complicated by overweight, multi-vessel lesions and left main coronary artery lesion have a higher incidence of NAFLD.