乳头状甲状腺微小癌颈部中央组淋巴结的转移规律及影响因素分析

目的 探讨乳头状甲状腺微小癌颈部中央组（Ⅵ区）淋巴结的转移规律和影响因素.方法 回顾性分析195例乳头状甲状腺微小癌患者的临床资料.患者均接受了双侧甲状腺全切除加双侧颈部中央组淋巴结清扫术治疗.结果 所有患者无手术及住院期间死亡,术后并发症发生率为2.1％（4/195）.中央组淋巴结转移发生率为35.4％（69/195）,影响淋巴结转移的因素包括年龄（OR=0.924）、性别（OR=0.213）、病灶数目（OR=2.208）和病灶总直径（OR =2.106）.结论 乳头状甲状腺微小癌可发生中央组淋巴结转移,当患者为年轻人或男性,病灶呈多灶性或总直径＞ 0.5 cm时转移发生率明显增加.

Metastasis rule and influence factors analysis of cervical central group lymph node in patients with papillary thyroid microcarcinoma

Objective To study the metastasis rule and influence factors of cervical central group （Ⅵ region） lymph node in patients with papillary thyroid microcarcinoma.Methods The clinical data of 195 patients with papillary thyroid microcarcinoma were analyzed retrospectively.All patients received bilateral thyroidectomy and bilateral cervical central group lymph node dissection.Results All patients died without surgery and hospitalization,the incidence of postoperative complications was 2.1％ （4/195）.The total incidence of cervical central group lymph node metastasis was 35.4％ （69/195）.Factors relating to cervical central group lymph node metastasis rate were：age （OR =0.924）,gender （OR =0.213）,the number of foci （OR =2.208） and the sum of the tumor diameters （OR =2.106）.Conclusions Patients with papillary thyroid microcarcinoma may suffer from lymph node metastasis of the cervical central group,and lymph node metastasis rate increases significantly in young or male patients,and when the lesions are multifocal or the sum of the tumor diameter ＞ 0.5 cm.