The “neurovascular unit approach” to evaluate mechanisms of dysfunctional autoregulation in asphyxiated newborns in the era of hypothermia therapy |
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| Authors: | Lina F. Chalak Takashi Tarumi Rong Zhang |
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| Affiliation: | 1. Department of Pediatrics, University of Texas, Southwestern Medical Center, Dallas, TX, United States;2. Department of internal medicine at University of Texas, Southwestern Medical Center, Dallas, TX, United States |
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| Abstract: | Despite improvements in obstetrical and neonatal care, and introduction of hypothermia as a neuroprotective therapy, perinatal brain injury remains a frequent cause of cerebral palsy, mental retardation and epilepsy. The recognition of dysfunction of cerebral autoregulation is essential for a real time measure of efficacy to identify those who are at highest risk for brain injury. |
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| Keywords: | HIE, hypoxic&ndash ischemic encephalopathy MRI, magnetic resonance imaging |
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