Amyloid goiter related with Crohn's disease: A rare association: Amyloid goiter secondary to Crohn's disease |
| |
Authors: | Ibrahim Ali Ozemir Cagri Bilgic Baris Bayraktar Sinan Aslan Ebru Zemheri Haydar Yalman Rafet Yigitbasi |
| |
Affiliation: | aIstanbul Medeniyet University, Goztepe Education and Research Hospital, Department of General Surgery, Istanbul, Turkey;bIstanbul Medeniyet University, Goztepe Education and Research Hospital, Department of Pathology, Istanbul, Turkey |
| |
Abstract: |
INTRODUCTIONAmyloid goiter (AG) is characterized by enlargement of the thyroid gland as a result of extensive amyloid deposition in a bilateral and diffuse manner.PRESENTATION OF CASEA 58-year-old male patient was diagnosed of Crohn''s Disease (CD). He was admitted to our clinic with complaint of respiratory distress and rapid growth swelling in the neck. Ultrasound examination revealed huge multinodular goiter on both sides of thyroid gland. We performed bilateral total thyroidectomy. Pathological evaluation revealed AG.DISCUSSIONAmyloid leads to degeneration in tissues, thereby disrupts the function of the relevant organs. It is important to distinguish AG from other reasons of goiter, particularly thyroid medullary cancer that can cause amyloid deposition in thyroid gland. Secondary amyloidosis frequently involves thyroid gland at microscopic level, but rarely causes goiter. An analysis of current literature revealed that only few cases of AG occurred secondary to CD. Herein we presented a case of AG who has rapidly growing goiter that associated with CD.CONCLUSIONAG must be kept in mind in case of rapidly growing goiter, especially in patients with chronic inflammatory bowel diseases. |
| |
Keywords: | Goiter Amyloidosis Crohn''s disease Amyloid goiter |
本文献已被 ScienceDirect 等数据库收录! |
|