| 浆液性卵巢癌的早期血清HE4的表达及诊断价值 |
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| 引用本文： | 范群. 浆液性卵巢癌的早期血清HE4的表达及诊断价值[J]. 海南医学院学报, 2013, 19(2): 227-229 |
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| 作者姓名： | 范群 |
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| 作者单位： | 广东省深圳市宝安区松岗人民医院妇产科,广东深圳,518105 |
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| 基金项目： | 中国高校医学期刊临床专项资金项目 |
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| 摘 要： | 目的:探讨血清人附睾蛋白4(HE4)在浆液性卵巢癌患者中的表达及其对早期患者的诊断价值。方法:分别检测卵巢癌、卵巢良性疾病及正常人各43例的血清HE4及CA125水平,并进行对比分析。结果:卵巢癌组血清HE4及CA125水平均显著高于其余两组(P<0.05);且HE4在卵巢癌患者中的阳性表达率显著高于CA125(P<0.05)。结论:HE4与CA125在卵巢癌患者中均可呈现明显增高的表达,但HE4对于卵巢癌的早期诊断更为敏感。
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| 关 键 词： | 浆液性卵巢癌 血清人附睾蛋白4 诊断价值 |
Expression and diagnostic value of HE4 level in early serous ovarian |
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| Abstract: | Objective: To discuss the expression and diagnostic value of HE4 level in early serous ovarian cancer.Methods: HE4 and CA125 of 43 patients with serous ovarian cancer,43 patients with benign ovarian diseases and 43 health people were detected and compared.Results: HE4 and CA125 of patients with serous ovarian cancer were significantly higher than the other two groups(P<0.05);and the positive rate of HE4 were significantly higher than CA125 in patients with serous ovarian cancer(P<0.05).Conclusions: HE4 and CA125 showed a significantly increased expression in ovarian cancer patients,but HE4 is more sensitive in early diagnosis of serous ovarian cancer. |
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| Keywords: | Serous ovarian cancer HE4 Diagnostic value |
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