食管癌患者围术期血清SCC-Ag、D-D、MICA及外周血T淋巴细胞亚群变化规律研究

目的:探讨食管癌患者围术期血清SCC-Ag、D-D、MICA及外周血T淋巴细胞亚群的变化规律。方法:选取2007年1月～2011年6月于本院进行手术治疗的120例食管癌患者为研究对象,将其术前、术后1d及3d的血清SCC-Ag、D-D、MICA及外周血T淋巴细胞亚群进行检测及比较。结果:食管癌患者术前、术后1d及3d的血清SCC-Ag、D-D、MICA呈现持续降低的趋势,外周血T淋巴细胞亚群也呈现逐渐改善的状态,术前分别与术后1d及3d比较,差异有统计学意义(P均<0.05)。结论:食管癌患者围术期血清SCC-Ag、D-D、MICA及外周血T淋巴细胞亚群呈现持续改善状态。

Change of serum SCC-Ag, D-D, MICA and peripheral blood T-lymphocyte subsets in perioperative esophageal cancer patients

Objective:To evaluate the change of the serum SCC-Ag,D-D,MICA and blood T-lymphocyte subsets in perioperative esophageal cancer patients.Methods:A total of 120 patients with esophageal cancer admitted from January 2007 to June 2011 in our hospital were chosen as research object.SCC-Ag,DD,MICA and peripheral blood T lymphocyte subsets before surgery,1 d and 3 d after surgery were tested and compared.Results:The serum SCC-Ag,D-D,MICA in perioperative esophageal cancer patients were gradually decreased,peripheral blood T lymphocyte subsets was gradually improved after surgery.There were significant differences in these indexes between that before surgery,1 d and 3 d after surgery(P<0.05).Conclusions:The serum SCC-Ag,D-D,MICA and peripheral blood T-lymphocyte subsets are improved after surgery.