头针不同行针手法对缺血性脑卒中血清中的VEGF、hs-CRP相关性的研究

目的:探讨头针不同行针手法对缺血性脑卒中血清中的VEGF、hs-CRP的意义。方法:选择我院2010年1月～2012年12月缺血性脑卒中患者200例,均神经内科常规药物治疗,分为4组,A组50例,采用捻转法,B组50例,采用留针法,C组50例,采用埋针法,D组50例,采用常规西医治疗,均为3疗程,于脑梗死治疗前及治疗后1、2、3疗程和对照组分别采用双抗夹心酶联免疫吸附法(ELLSA法)测定VEGF及免疫透射比浊法测定hs-CRP水平,并讨论二者的相关性。结果:四组中VEGF、hs-CRP蛋白表达:治疗后与治疗前比较,均有显著性差异,P<0.01;治疗后A组、B组、C组分别与D组比较,均有显著性差异,P<0.05;第三疗程,C组与其它三组分别比较,均有显著性差异,P<0.01;治疗后三个疗程中VEGF、hs-CRP蛋白表达相关性分析,均有明显负相关性(均P<0.05)。结论:VEGF、hs-CRP水平变化与脑梗死有着密切关系,其升高、降低水平与病变程度有关系。

Effect of different method of scalp acupuncture on VEGF, hs-CRP of patients with cerebral arterial thrombosis

Objective: To explore different method of scalp acupuncture on VEGF,hs-CRP of patients with cerebral arterial thrombosis.Methods: A total of 200 cases with cerebral arterial thrombosis admitted from January 2010-December 2012 were selected.They were treated by neurological conventional drug.They were divided into four groups,with 50 cases in each group: patients in group A were treated by twirling method,group B by needle-retaining method,group C by needle-embedding therapy,and group D by conventional western medicine.All patients were treated for 3 courses.VEGF and hs-CRP were measured by ELISA and immunological transmission turbidimetry,respectively before treatment,at the 1st,2nd and 3rd course,and their correlation was analyzed.Results: There were significant differences in VEGE and hs-CRP between these before and after treatment(P<0.01),the difference was also significant between group D and other three groups(P<0.05).At the 3rd course,there were significant differences in two indexes between group C and other three groups(P<0.01).VEGF and hs-CRP were negatively correlated with cerebral arterial thrombosis(P<0.05).Conclusions:VEGF and hs-CRP were closely related with cerebral arterial thrombosis,and is correlated with severity.