| 脂联素及其受体与胰岛素抵抗的研究进展 |
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| 引用本文： | 周瑞秀,王静,逄力男.脂联素及其受体与胰岛素抵抗的研究进展[J].医学综述,2008,14(4):515-517. |
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| 作者姓名： | 周瑞秀 王静 逄力男 |
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| 作者单位： | 潍坊医学院内科学教研室,山东,潍坊,261042 |
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| 摘 要： | 脂联素是来源于脂肪组织的脂肪因子之一,脂联素与胰岛素抵抗相关疾病,如肥胖、代谢综合征、2型糖尿病、动脉粥样硬化有关。脂联素受体介导了脂联素的各种生物学效应,脂联素基因多态性可能会影响脂联素的表达水平及其功能,研究脂联素基因多态性、脂联素受体可以更好地理解脂联素作用的分子机制。
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| 关 键 词： | 胰岛素抵抗 2型糖尿病 脂联素 脂联素受体 |
| 文章编号： | 1006-2084（2008）04-0515-03 |
| 收稿时间： | 2007-07-24 |
| 修稿时间： | 2007-10-24 |
Progress about Relationship of Insulin Resistance with Adiponectin and its Receptors |
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| ZHOU Rui-xiu,WANG Jing,PANG Li-nan.Progress about Relationship of Insulin Resistance with Adiponectin and its Receptors[J].Medical Recapitulate,2008,14(4):515-517. |
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| Authors: | ZHOU Rui-xiu WANG Jing PANG Li-nan |
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| Institution: | ZHOU Rui-xiu,WANG Jing,PANG Li-nan.(Teaching Institute of Internal Medicine,Weifang Medical College,Weifang 261042,China) |
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| Abstract: | Adiponectin is one of the adipoeytokines that is derived from adipose tissue. Adiponectin is related to some diseases associated with insulin resistance, merabolic syndrome, type 2 diabetes, and athcrosclerosis.. Its receptors mediate all kinds of biological function of adiponectin. Adiponectin gene polymorphism perhaps affects the expression and function of adiponectin. Studies about its gene polymorphism and receptor will be helpful to recognize the molecular mechanism of action of adiponectin. |
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| Keywords: | Insulin resistance Type2 diabetes mellitus Adiponectin Adiponectin receptors |
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