Protection of Epithelial Barrier Function by the Crohn's Disease Associated Gene Protein Tyrosine Phosphatase N2期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Protection of Epithelial Barrier Function by the Crohn's Disease Associated Gene Protein Tyrosine Phosphatase N2

Authors:	Michael Scharl Gisela Paul Achim Weber Barbara C. Jung Michael J. Docherty Martin Hausmann Gerhard Rogler Kim E. Barrett Declan F. McCole

Affiliation:	^?Division of Gastroenterology, University of California, San Diego, School of Medicine, La Jolla, California;^‡Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland;^§Department of Pathology, Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland

Abstract:

Keywords:	Abbreviations used in this paper: AICAR, 5-aminoimidazole-4-carboxamide-1-β-d-ribonucleoside AMPK, adenosine monophosphate-activated protein kinase CC, compound C CD, Crohn's disease FITC, fluorescein isothiocyanate IBD, inflammatory bowel disease IEC, intestinal epithelial cells IFN-γ, interferon γ mRNA, messenger RNA PTP, protein tyrosine phosphatase PTPN2, protein tyrosine phosphatase N2 siRNA, small interfering RNA SNP, single nucleotide polymorphism STAT, signal transducer and activator of transcription TC-PTP, T-cell protein tyrosine phosphatase TER, transepithelial electrical resistance TNF, tumor necrosis factor UC, ulcerative colitis
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