| 芒果苷对小鼠抗应激作用的实验研究 |
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| 引用本文： | 韦健全,郑子敏,潘勇,许小林,薛强,黄斌学,赖术,黄增琼. 芒果苷对小鼠抗应激作用的实验研究[J]. 右江民族医学院学报, 2003, 25(5): 610-612 |
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| 作者姓名： | 韦健全 郑子敏 潘勇 许小林 薛强 黄斌学 赖术 黄增琼 |
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| 作者单位： | 右江民族医学院药理学教研室,广西百色533000 |
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| 摘 要： | 目的 观察芒果苷对小鼠的抗应激作用。方法 予不同浓度、剂量的芒果苷和淀粉蒸馏水分别给小鼠灌胃 1h后 ,分组进行负重游泳、耐缺氧、耐低温的应激实验 ,实验过程中测定小鼠血清超氧化物歧化酶 (SOD )活力、丙二醛(MDA)含量的变化。结果 予芒果苷的小鼠在不同的抗应激实验中的生存时间均比对照组延长 (P均 <0 .0 1) ,血清中SOD活力上升、MDA含量下降 (P <0 .0 1或 0 .0 5 )。结论 芒果苷具有一定的抗应激作用。
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| 关 键 词： | 芒果苷 应激 丙二醛 超氧化物歧化酶 |
| 文章编号： | 1001-5817(2003)05-0610-03 |
| 修稿时间： | 2003-05-27 |
An Experimental Study of Anti-stress Effects of Mangiferin in Mice |
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| WEI Jian-quan,ZHENG Zi-min,PAN Yong,XU Xiao-lin,XUE Qiang,HUANG Bin-xue,LAI Shu,HUANG Zeng-qiong. An Experimental Study of Anti-stress Effects of Mangiferin in Mice[J]. Journal of Youjiang Medical College For Nationalities, 2003, 25(5): 610-612 |
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| Authors: | WEI Jian-quan ZHENG Zi-min PAN Yong XU Xiao-lin XUE Qiang HUANG Bin-xue LAI Shu HUANG Zeng-qiong |
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| Abstract: | Objective To observe the anti-stress effects of Mangiferin in mice. Methods One hour after different concentrations and doses of Mangiferin and distilled water were administered using Gavage method, mice were divided into groups for anti-stress tests like loaded swimming, resistance to lack of oxygen and low temperature to observe changes of superoxide dismutase (SOD) vitality and concentrations of Malondialdehyde (MDA). Results The survival time of the tested mice were longer than the control groups (P<0.01) with sera SOD vitality increased and MDA concentration decreased (P<0.01 or 0.05). Conclusion Mangiferin had certain anti-stress actions. |
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| Keywords: | Mangiferin anti-stress MDA SOD |
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